Development of a Completely New PFOS Alternative with Lower Surface Tension for Minimizing the Environmental Burden  

作　　者：ZHOU Zhen GUO Rui CHEN Bolei WANG Ling CAO Huiming WEI Cuiyun HU Ming ZHAN Yuhang LI Shutao WANG Yawei LIANG Yong 

机构地区：[1]Hubei Key Laboratory of Environmental and Health Effects of Persistent Toxic Substances,School of Environment and Health,Jianghan University,Wuhan,430056,P.R.China [2]Hubei Hengxin Chemical Co.,Ltd.,Yingcheng,432400,P.R.China [3]State Key Laboratory of Environmental Chemistry and Ecotoxicology,Research Center for Eco-Environmental Sciences,Chinese Academy of Sciences,Beijing,100085,P.R.China

出　　处：《Chemical Research in Chinese Universities》2023年第3期408-414,共7页高等学校化学研究（英文版）

基　　金：supported by the National Natural Science Foundation of China(Nos.21707049,21507044,21806058,21906069,21477049);the China Postdoctoral Science Foundation(No.2019M660185).

摘　　要：Improving the technical performance of related industrial products is an efficient strategy to reducing the application quantities and environmental burden for toxic chemicals.A novel polyfluoroalkyl surfactant potassium 1,1,2,2,3,3,4,4-octafluoro-4-(perfluorobutoxy)butane-1-sulfonate(F404)was synthesized by a commercializable route.It had a surface tension(γ)of 18.2 mN/m at the critical micelle concentration(CMC,1.04 g/L),significantly lower than that of perfluorooctane sulfonate(PFOS,ca.33.0 mN/m,0.72 g/L),and exhibited remarkable suppression of chromium-fog at a dose half that of PFOS.The half maximal inhibitory concentration(IC_(50))values in HepG2 cells and the lethal concentration of 50%(LC_(50))in zebrafish embryos after 72 hpf indicated a lower toxicity for F404 in comparison to PFOS.In a UV/sulphite system,89.3%of F404 were decomposed after 3 h,representing a defluorination efficiency of 43%.The cleavage of the ether C—O bond during the decomposition would be expected to form a short chain·C_(4)F_(9) as the position of the ether C—O in the F404 fluorocarbon chains is C4—O5.The ether unit is introduced in the perfluoroalkyl chain to improve water solubility,biocompatibility and degradation,thereby minimizing the environmental burden.

关 键 词：Perfluorooctane sulfonate(PFOS) Surface tension Chromium-fog inhibitor PERFLUOROPOLYETHER 

分 类 号：O62[理学—有机化学]