甲状腺良性结节射频消融短期疗效及相关影响因素分析  

Analysis of Short-Term Efficacy and Related Influencing Factors of Radiofrequency Ablation of ThyroidBenign Nodules

作　　者：侯文颖 杨敬春[1] 常莹[1] 马佳[1] 杜岚[1] 冷振鹏[1] Hou Wenying;Yang Jingchun;Chang Ying;Ma Jia;Du Lan;Leng Zhenpeng(Department of Ultrasound,Xuanwu Hospital,Capital Medical University,Beijing 100053,China)

机构地区：[1]首都医科大学宣武医院超声诊断科,北京市100053

出　　处：《中国超声医学杂志》2023年第6期622-625,共4页Chinese Journal of Ultrasound in Medicine

摘　　要：目的探讨超声引导下射频消融(RFA)治疗甲状腺良性结节短期疗效及影响因素。方法选取单次RFA治疗甲状腺良性结节患者的临床资料,分析RFA治疗前后结节最大径、体积变化及治疗后短期结节体积缩小率(VRR)及总有效率;分析术前结节直径、体积、血供及消融时间、功率、能量等因素,以及与VRR的相关性;对比结节成分、有无钙化、血流对VRR的影响。结果RFA治疗后,短期内结节VRR组间比较,除3个月与6个月外均有统计学意义(P<0.001),治疗后3个月、6个月总有效率分别为91%及95.6%。RFA治疗前后结节体积及直径比较均有统计学意义(P<0.001);结节术前最大径、体积与VRR均呈负相关(r_(s)=-0.423、-0.428,P<0.05);血供、成分、功率、能量与VRR无明显相关性(P>0.05);治疗6个月后不伴钙化者较钙化者结节疗效显著,VRR分别为(87.83±41.04)%、(61.16±65.68)%。结论甲状腺良性结节术后3个月及6个月吸收率良好,不伴钙化者较钙化者结节疗效显著。Objective To explore the short-term efficacy and influencing factors of ultrasound-guided radiofrequency ablation(RFA)treatment in benign thyroid nodules.Methods We selected the clinical data of patients with benign thyroid nodules whom treated with single RFA,to analyze the changes in the maximum diameter and volume of the nodules before and after RFA treatment,as well as the volume reduction rate(VRR)and total effective rate after treatment,and analyze the factors such as diameter,volume,blood supply,time,ablation power,energy and their correlation with VRR.We also compared the influence of nodule composition,calcification and blood flow on VRR.Results After RFA treatment,there was statistical difference between the VRR groups of short-term nodules except for the 3 and 6 months(P<0.0o1);At the three months and six months after treatment,the total effective rate was 91%and 95.6%respectively.The volume and diameter of nodules before and after RFA treatment were significantly different(P<0.001).The maximum diameter and volume of nodules before operation were negatively correlated with the curative effect(r_(s)=-0.423、-0.428,P<0.05).There was no significant correlation between blood supply,composition,power,time and energy(P>0.05).After 6 months of treatment,the effective of patients without calcification were significantly better than those with calcification,with the VRR of(87.83±41.04)%and(61.16±65.68)%respectively.Conclusions The absorption rate of small thyroid benign nodules are good in 3 and 6 months after operation.The effect of nodules without calcification is significantly better than that of nodules with calcification.

关 键 词：甲状腺结节 射频消融 吸收率 超声 

分 类 号：R445.1[医药卫生—影像医学与核医学] R581[医药卫生—诊断学]