自体富血小板凝胶治疗难愈性糖尿病足溃疡的临床疗效分析  

Clinical Efficacy Analysis of Autologous Platelet-rich Gel for Refractory Diabetic Foot Ulcers

作　　者：曾泓铭 凌小元 郑琴秀 ZENG Hongming;LING Xiaoyuan;ZHENG Qinxiu(Department of Endocrinology,Qionghai People's Hospital,Qionghai,Hainan Province,571400 China)

机构地区：[1]琼海市人民医院内分泌科,海南琼海571400

出　　处：《糖尿病新世界》2023年第8期168-170,174,共4页Diabetes New World Magazine

摘　　要：目的探讨难愈性糖尿病足溃疡患者应用自体富血小板凝胶治疗的临床价值。方法选取2021年7月—2022年9月琼海市人民医院接收的62例难愈性糖尿病足溃疡患者作为研究对象,随机分为研究组与对照组,每组31例。对照组为常规的碘伏治疗,研究组为自体富血小板凝胶治疗,比较两组临床疗效、溃疡愈合速率及愈合时间,并对两组不良反应进行分析对比。结果研究组总有效率高于对照组,差异有统计学意义(P<0.05)。研究组溃疡愈合速率较对照组高,且愈合时间较对照组短,差异有统计学意义(P<0.05)。两组不良反应总发生率对比,差异无统计学意义(P>0.05)。结论在难愈性糖尿病足溃疡患者的治疗中,采用自体富血小板凝胶治疗,效果较好,可加速患者创面预后,提高治愈率,且治疗时间明显缩短,安全性较高,在减轻患者痛苦的同时,可降低经济负担。Objective To investigate the clinical value of applying autologous platelet-rich gel for the treatment of patients with refractory diabetic foot ulcers.Methods 62 patients with refractory diabetic foot ulcers admitted to Qionghai People's Hospital from July 2021 to September 2022 were selected as the study subjects and randomly divided into a study group and a control group,with 31 cases in each group.The control group was conventional iodophor treatment,and the study group was autologous platelet-rich gel index.The clinical efficacy,ulcer healing rate and healing time of the two groups were compared,and the adverse effects of the two groups were analyzed and compared.Results The total effective rate of the research group was higher than that of the control group,and the difference was statistically significant(P<0.05).The ulcer healing rate of the study group was higher than that of the control group,and the healing time was shorter than that of the control group,the difference was statistically significant(P<0.05).There was no statistically significant difference in the total incidence of adverse reactions between the two groups(P>0.05).Conclusion In the treatment of patients with refractory diabetic foot ulcers,the use of autologous platelet-rich gel is more effective,can accelerate the prognosis of patients'wounds and improve their healing rate,and the treatment time is significantly shorter and safer,which can reduce the economic burden of patients while alleviating their pain.

关 键 词：难愈性 糖尿病足溃疡 自体富血小板凝胶 临床疗效 愈合时间 不良反应 

分 类 号：R4[医药卫生—临床医学]