MXene/过氧化物复合材料的制备及抗菌性能研究  

Preparation and synergistic antibacterial properties of MXene/peroxide composites

作　　者：田煜 张姝婷 邓怡[1] 廖立[1] TIAN Yu;ZHANG Shu-ting;DENG Yi;LIAO Li(School of Chemical Engineering,Sichuan University,Chengdu 610065,China)

机构地区：[1]四川大学化学工程学院,四川成都610065

出　　处：《应用化工》2023年第6期1619-1625,共7页Applied Chemical Industry

基　　金：国家自然科学基金(81801848);四川省重点研发项目(2023YFG0248)。

摘　　要：针对细菌感染,传统的抗生素疗法易使细菌产生耐药性,迫切需要探索一种脱离抗生素的高效安全的抗菌方法。为此,开发了一种由碳化钛(MXene)与铜铁过氧化物(CFps)通过静电结合形成的光热及双动力协同抗菌的智能复合材料(MXene-CFps)。采用扫描电镜、X射线衍射、能谱仪等分析了材料的组成和形貌结构。光热实验、ROS检测实验以及抗菌实验结果显示该复合材料在近红外光的辐照下,表现出优异的光热和光动力的性能,且其中的自供给芬顿体系也可产生过氧化氢和羟基自由基,对金黄色葡萄球菌(S.aureus)及大肠杆菌(E.coil)表现出高效且持久的杀菌效果。In response to bacterial infections,traditional antibiotic therapies predispose bacteria to drug resistance,and it is urgent to explore a highly effective and safe antibacterial method of detachment from antibiotics.Therefore,a smart composite(MXene-CFps)consisting of titanium carbide(MXene)combined with copper iron peroxides(CFps)via electrostatic combination for photothermal and dual dynamic synergistic antibacterial was developed.SEM,X-ray diffraction,spectroscopy were used to analyze the composition and morphology.Meanwhile,the results of photothermal experiment,ROS detection experiment as well as antibacterial experiment revealed that the composite exhibited excellent photothermal and photodynamic performance under irradiation of NIR light.Plus,the self-supplied Fenton system in the material system can produce hydrogen peroxide and hydroxyl free radicals,which has a highly effective and lasting bactericidal effect on S.aureus and E.coli.

关 键 词：近红外光 复合材料 MXene 光治疗 化动力疗法 协同抗菌治疗 

分 类 号：TQ13[化学工程—无机化工] TB34[一般工业技术—材料科学与工程] R318.51[医药卫生—生物医学工程]