2015-2021年我国丙型肝炎病例报告与哨点监测分析  

Hepatitis C case report and sentinel surveillance in China from 2015 to 2021

作　　者：李健[1] 庞琳[1] 李东民[1] 丁国伟[1] 叶少东[1] 葛琳[1] 汤后林[1] 刘中夫[1] 周宇辉 LI Jian;PANG Lin;LI Dongmin;DING Guowei;YE Shaodong;GE Lin;TANG Houlin;LIU Zhongfu;ZHOU Yuhui(National Center for STD/AIDS Control and Prevention,Chinese Center for Disease Control and Prevention,Beijing 102206,China;Chinese Center for Disease Control and Prevention,Beijing 102206)

机构地区：[1]中国疾病预防控制中心性病艾滋病预防控制中心,北京102206 [2]中国疾病预防控制中心,北京102206

出　　处：《中国艾滋病性病》2023年第6期634-638,共5页Chinese Journal of Aids & STD

摘　　要：目的分析WHO提出消除病毒性肝炎目标以来我国丙肝病例报告与哨点监测情况,为下一步推进我国消除丙肝工作提供参考依据。方法利用丙肝病例报告数据、艾滋病哨点和丙肝人群哨点监测数据以及丙肝医院哨点监测数据,采用描述性分析方法,分析2015-2021年新报告丙肝病例人口学特征、不同监测人群历年抗-HCV阳性比例,以及2017-2021年医院哨点监测人群抗-HCV检测人数、抗-HCV阳性比例、HCV核酸检测比例和抗病毒治疗比例等。结果2015-2021年全国历年报告丙肝病例数均在20万以上,40岁以上年龄组丙肝病例数占比超过75.00%,职业主要以农民和家务及待业为主。在所有监测人群中,吸毒者抗-HCV阳性比例最高,由2015年的35.85%降低到2021年的25.30%。医院就诊人群的抗-HCV阳性比例由2017年的1.97%降至2021年的1.67%,新报告病例HCV核酸检测比例由55.13%提高至66.34%,直接抗病毒药物(DAAs)治疗比例由9.42%提高至14.30%。结论世界卫生组织提出消除病毒性肝炎愿景后,我国丙肝核酸检测、抗病毒治疗等防治工作取得了积极进展,为实施消除丙肝公共卫生危害行动奠定了基础,但是丙肝诊断发现、抗病毒治疗等核心指标距消除目标差距较大,亟需全面落实消除丙肝各项防治措施和保障措施。Objective To analyze hepatitis C case report and sentinel surreillance in China since the World Health Organization proposed the goal of eliminating viral hepatitis,and to provide a reference basis for further promoting the elimination of hepatitis C in China.Methods Descriptive analysis was used to analyze the demographic characteristics of newly reported hepatitis C cases from 2015 to 2021.The proportions of anti-HCV positive in different monitoring populations were described over the years.Descriptive analysis was also used to analyze the number of anti-HCV tested,the proportion of anti-HCV positive,the proportion of confirmed hepatitis C cases,and the proportion of antiviral treatment in the hospital sentinel surveillance population from 2017 to 2021.Results The number of hepatitis C cases reported in China was over 200,000 every year from 2015 to 2021.More than 75.00%of hepatitis C cases were over 40 years old.The occupations were mainly farmers,houseworkers,and unemployed.Among all monitored populations,the anti-HCV positive rate among drug users was the highest and decreased from 35.85%in 2015 to 25.30%in 2021.The anti-HCV positive rate among hospital visitors decreased from 1.97%in 2017 to 1.67%in 2021.The proportion of confirmed newly reported cases increased from 55.13%to 66.34%,and the proportion of DAAs treatment increased from 9.42%to 14.30%.Conclusions After the World Health Organization proposed the vision of eliminating viral hepatitis,positive progress has been made in the prevention and treatment of hepatitis C in China,including the availability of nucleic acid testing and antiviral treatment,which laid the foundation for the implementation of actions to eliminate the public health hazards of hepatitis C.However,core indicators such as hepatitis C detection and antiviral treatment still have gaps to reach the elimination goal.It is urgent to fully implement prevention,control,and safeguard measures to eliminate hepatitis C.

关 键 词：丙型肝炎 流行特征 防治进展 

分 类 号：R512.91[医药卫生—内科学]