The Regulatory Effect of Braided Silk Fiber Skeletons with Differential Porosities on In Vivo Vascular Tissue Regeneration and Long-Term Patency  

作　　者：Xili Ding Weirong Zhang Peng Xu Wentao Feng Xiaokai Tang Xianda Yang Lizhen Wang Linhao Li Yan Huang Jing Ji Diansheng Chen Haifeng Liu Yubo Fan 

机构地区：[1]School of Engineering Medicine,Beihang University,Beijing 100083,China [2]Key Laboratory of Biomechanics and Mechanobiology(Beihang University),Ministry of Education,Bejing Advanced Innovation Center for Biomedical Engineering,School of Biological Science and Medical Engineering,Beihang University,Beijing 100083,China 3 [3]eRobot Institute,School of Mechanical Engineering and Automation,Beihang University,Beijing 100083,China

出　　处：《Research》2023年第2期247-264,共18页研究（英文）

基　　金：The authors graciously acknowledge professor Deling Kong's lab for their assistance with the animal experiments.This project was supported by the National Natural Science Foundation of China(T2288101,32000968,32071359,11827803,and U20A20390);Beijing Natural Science Foundation(M22026);Fundamental Research Funds for the Central Universities,and 111 Project(B13003).

摘　　要：The development of small-diameter vascular grafts that can meet the long-term patency required for implementation in clinical practice presents a key challenge to the research field.Although techniques such as the braiding of scaffolds can offer a tunable platform for fabricating vascular grafts,the effects of braided silk fiber skeletons on the porosity,remodeling,and patency in vivo have not been thoroughly investigated.

关 键 词：field SKELETON thoroughly 

分 类 号：O15[理学—数学]