中药熏洗治疗早期肛裂的Meta分析  

A Meta-analysis of treating early anal fissure by TCM medicine fumigation and washing therapy

作　　者：尹红妍 周天羽[2] YIN Hongyan

机构地区：[1]辽宁中医药大学,辽宁沈阳110000 [2]辽宁中医药大学附属医院,辽宁沈阳110000

出　　处：《中医临床研究》2023年第17期110-116,共7页Clinical Journal Of Chinese Medicine

基　　金：辽宁省自然科学基金(2020-MS-226)。

摘　　要：目的:系统评价中药汤剂熏洗对早期(急性)肛裂的治疗效果,为早期(急性)肛裂的临床治疗提供循证依据。方法:通过计算机检索中国期刊全文数据库、维普数据库、万方数据库、中国生物医学文献数据库,收集以上数据库自建库起至2022年3月关于中药汤剂熏洗治疗早期(急性)肛裂的随机对照试验研究。其中观察组予中药熏洗治疗,对照组予西药坐浴治疗。筛选文献,并运用RevMan 5.3软件进行Meta分析。结果:最终纳入14项随机对照试验研究,共包含患者1182例。Meta分析结果显示,观察组和对照组的总有效率差异有统计学意义(P<0.05)。治疗结束后,两组疼痛评分、便血评分、裂口愈合时间、中医证候积分的差异有统计学意义(P<0.05)。结论:中药汤剂熏洗治疗早期(急性)肛裂的疗效较西药显著,且在改善疼痛评分、便血评分、裂口愈合时间、中医证候积分等方面均优于西药治疗。Objective:To systematically evaluate the therapeutic effect of TCM medicine fumigation and washing on early(acute)anal fissure,so as to provide a evidence-based basis for the clinical treatment of early(acute)anal fissure.Methods:In CNKI,VIP,Wanfang Database,China biomedical medicine literature database,etc.,the studies from initial stage of the above databases to March 2022 on randomized controlled trial of TCM medicine fumigating and washing therapy in the treatment of early(acute)anal fissure were collected to select the literature that met the criteria.The observation group was given TCM medicine fumigating and washing therapy,and the control group took Western medicine sitz bath.A Meta-analysis was performed by RevMan 5.3 software.Results:Fourteen randomized controlled trials were included finally,with 1182 cases.The meta-analysis showed that there was a statistically significant difference in the total efficiency between the two groups.After treatment,the differences between the two groups in the pain score,hematoxia score,fracture healing time,and TCM syndrome score were all statistically significant(P<0.05).Conclusion:The therapeutic effect of TCM fumigation and washing therapy on early anal fissure was significantly better than that of Western medicine,and it was superior to Western medicine in ameliorating pain score,hematochezia score,fissure healing time and TCM syndrome score.

关 键 词：早期肛裂 中药汤剂熏洗 META分析 随机对照试验 

分 类 号：R657.14[医药卫生—外科学]