40-69岁居民肥胖类型与心血管危险因素的关联分析  

Analysis of the association between types of obesity and cardiovascular risk factors in residents aged 40 to 69 years

作　　者：黄飞[1] 朱进华 华召来 施秋平 陶司磊 仝海员[3] 周金意[4] 冯祥 HUANG Fei;ZHU Jin-hua;HUA Zhao-lai;SHI Qiu-ping;TAO Si-lei;TONG Hai-yuan;ZHOU Jin-yi;FENG Xiang(Department of Laboratory,Yangzhong People’s Hospital,Jiangsu,Yangzhong 212200,China;不详)

机构地区：[1]扬中市人民医院检验科,江苏扬中212200 [2]扬中市肿瘤防治研究所,江苏扬中212200 [3]扬中市疾病预防控制中心慢性病防制科 [4]江苏省疾病预防控制中心慢性病防制所

出　　处：《现代预防医学》2023年第13期2305-2310,2343,共7页Modern Preventive Medicine

基　　金：国家重点研发计划(2016YFC0901400,2016YFC1302800);中国消化道早癌医师共同成长计划(GTCZ-2021-JS-32-0001);镇江市重点研发计划—社会发展(SH2022051)。

摘　　要：目的分析扬中市居民体质指数(BMI)和腰围(WC)与心血管危险因素(CRFs)的相关性。方法采用多阶段分层整群抽样方法,选取40~69岁居民作为调查对象进行现场调查。对数据进行描述性分析、t检验、方差分析、χ^(2)检验、多分类无序和二分类logistic回归分析。结果6581名研究对象中,高血压前期、高血压、糖尿病前期、糖尿病、高总胆固醇(TC)、高甘油三酯(TG)、高低密度脂蛋白胆固醇(LDL-C)、低高密度脂蛋白胆固醇(HDL-C)和血脂异常的患病率分别为25.54%、67.19%、11.09%、12.66%、8.92%、28.69%、0.80%、9.30%和38.70%。多分类无序/二分类logistic回归分析结果显示,调整混杂变量后,超重(OR:1.220~2.503)、肥胖(OR:1.641~3.705,高血压前期和高TC除外)、中心性肥胖(OR:1.210~2.266,高LDL-C除外)均是CRFs的独立危险因素(均P<0.05)。与单一肥胖类型相比,复合型肥胖人群(OR:1.634~3.128)患高血压、糖尿病前期、糖尿病和血脂异常的风险更高(均P<0.05)。除高血压前期和高血压外,腰围每增加一个标准差的OR值均高于BMI。结论扬中市中老年人超重、肥胖和中心性肥胖均是高血压、糖尿病和血脂异常等CRFs的独立危险因素,其中复合型肥胖人群风险更高,且WC与多数CRFs关联要强于BMI。Objective To analyse the correlation between body mass index,waist circumference and cardiovascular risk factors(CRFs)in residents in Yangzhong city.Methods Residents aged 40-69 years were selected for field investigation using a multistage stratified clustering sampling method.The descriptive analysis,student’s t-test,ANOVA,χ^(2) test,multi-categorical unordered and binary logistic regression were performed to analyse data.Results Of the 6581 subjects,the prevalence of pre-hypertension,hypertension,pre-diabetes,diabetes,high total cholesterol(TC),high triglyceride(TG),high low-density lipoproteinemia(LDL-C),low high-density lipoproteinemia(HDL-C)and dyslipidaemia was 25.54%,67.19%,11.09%,12.66%,8.92%,28.69%,0.80%,9.30%,and 38.70%,respectively.Results of multi-categorical unordered and binary logistic regression analyses showed that overweight(OR:1.220-2.503),obesity(OR:1.641-3.705,except pre-hypertension and high TC),and central obesity(OR:1.210-2.266,except high LDL-C)were all independent risk factors for CRFs after adjusting for confounding variables(all P<0.05).Compound obesity(OR:1.634-3.128)was associated with a higher risk of hypertension,pre-diabetes,diabetes,and dyslipidaemia compared to a single obesity type(all P<0.05).ORs per standard deviation increase in WC were higher than BMI,except for pre-hypertension and hypertension.Conclusion Being overweight,obesity,and central obesity are all independent CRFs,including hypertension,diabetes and dyslipidaemia in middle-aged and elderly people in Yangzhong city,with a higher risk in the compound obese population.Besides,WC has stronger associations with most CRFs than BMI.

关 键 词：心血管危险因素 全身型肥胖 中心性肥胖 关联 

分 类 号：R54[医药卫生—心血管疾病] R589.2[医药卫生—内科学]