滋阴补肾方治疗肾阴虚型少弱精子症临床疗效观察  

Clinical therapeutic effect of Ziyinbushen prescription for treating the symptoms of patients with oligospermia or asthenospermia caused by kidney yin deficiency

作　　者：邓国艳 许芮豪 胡那顺 宋阳光 包金花[3] 孙立文 呼格吉乐图[3] 斯琴其木格 许玉萍 萨日娜 霍桂荣 王香兰 马光 张斌 王尚明 张树成 DENG Guoyan;XU Ruihao;HU Naishun;SONG Yangguang;BAO Jinhua;SUN Liwen;HUGE Jiletu;Siqinqimuge;XU Yuping;Sarina;HUO Guirong;WANG Xianglan;MA Guang;ZHANG Bin;WANG Shangming;ZHANG Shucheng(Tongliao Obstetrics and Gynecology Hospital,Tongliao,Nei Monggol Autonomous Region;National Research Institute for Family Planning,Beijing;Hospital of Inner Mongolia MINZU University,Tongliao,Nei Monggol Autonomous Region)

机构地区：[1]内蒙古自治区通辽市妇产医院,028000 [2]国家卫生健康委科学技术研究所 [3]内蒙古民族大学附属医院

出　　处：《中国计划生育学杂志》2023年第7期1527-1531,共5页Chinese Journal of Family Planning

基　　金：国家重点基础研究发展计划(973计划,2010CB530403);国家自然科学基金(90409016);国家科技基础性工作专项(2013FY110500)。

摘　　要：目的:观察自拟滋阴补肾方药对肾阴虚型少弱精子症患者精液质量及肾阴虚常见症状的治疗效果。方法:选取2018-2021年本院接受治疗的男性少弱精子症患者233例,服用自拟滋阴补肾方药3个月,采用自身对照方法对服药前、服药和停药3个月进行精液质量及肾阴虚常见症状分析。结果:服药3个月后精子总活力(PR+NP)、前向运动精子率(PR)、精子浓度、排精总数和精液量均明显增加(P<0.05);治疗少弱精子症的治愈率71.8%、临床显效率17.6%、有效率6.0%、无效率4.7%;中医肾阴虚单证变化的临床控制率和总有效率分别在遗精为66.5%和90.4%、早泄为40.2%和79.3%、五心烦热为61.6%和90.8%、盗汗为60.1%和96.2%、腰膝酸软为54.9%和96.0%、头晕为59.4%和91.4%、耳鸣为60.7%和95.5%,与治疗前比较均有明显改善(P<0.01)。结论:自拟滋阴补肾生精方药对肾阴虚型少弱精子症患者具有明确提高精子活力、精子数目和精液量的作用,改善患者遗精、早泄、五心烦热、盗汗、腰膝酸软、头晕、耳鸣等肾阴虚症状,并在停药后具有后续效应。Objective:To observe the therapeutic effect of Ziyinbushen prescription for treating the patients with oligospermia or asthenospermia caused by kidney yin deficiency.Methods:233patients with oligospermia or asthenospermia from 2018to 2021were selected in this study.These patients had been treated by Ziyinbushen prescription for three months.Self-controlled trial was conducted on the analysis of the semen quality and the common symptoms of renal yin deficiency of these patients before,during,and after treatment.Results:The total sperm motility(PR+NP),the percentage of PR,sperm concentration,and total sperm output of the patients after treatment for three months had increased significantly(P<0.05).The significant efficiency rate,the effective rate,the inefficiency rate,and the total clinical cure rate of the treatment of the patients with oligospermia or asthenospermia were 17.6%,6.0%,4.7%,and 71.6%,respectively.The clinical control rate and the total effective rate of the changes of single symptom in traditional Chinese medicine of the spermatorrhea of the patients were 66.5%and 90.4%,which of the premature ejaculation of the patients were 40.2%and 79.3%,which of the five upset fever of the patients were 61.6%and 90.8%,which of the night sweat of the patients were 60.1%and 96.2%,which of the lumbar and knee acidness of the patients were 54.9%and 96.0%,which of the dizziness of the patients were 59.4%and 91.4%,and which of the tinnitus of the patients were 60.7%and 95.5%.And the spermatorrhea,the premature ejaculation the five upset fever,the night sweat,the lumbar and knee acidness,the dizziness,and the tinnitus of the patients after treatment had improved significantly(P<0.01).Conclusion:The Ziyinbushen prescription by self designed for treating patients with oligospermia or asthenospermia have the confirmative function of promoting the sperm motility,sperm count,and semen volume of the patients,and which can improve the spermatorrhea,premature ejaculation,five frustrating heat,night sweats,waist and knee pain,di

关 键 词：少精症 弱精症 肾阴虚 五子衍宗丸 金匮肾气丸 临床疗效 

分 类 号：R277.5[医药卫生—中医学]