机构地区:[1]北京中医药大学,北京100029 [2]中国中医科学院广安门医院,北京100053 [3]中日友好医院,北京100029
出 处:《中国药学杂志》2023年第11期1037-1044,共8页Chinese Pharmaceutical Journal
摘 要:目的通过文献计量学方法,分析Web of Science(WoS)核心合集数据库中近20年绝经后冠心病治疗相关研究的热点内容和发展趋势,为后续深入探究该领域提供参考。方法以WoS数据库作为文献来源,查询近20年与绝经后冠心病治疗相关的英文文献,通过CiteSpace分别进行年度发文量、合作网络分析、关键词分析和共被引可视化分析。结果初步得到文献1617篇,根据纳排标准,最终纳入文献329篇。该领域英文发文量整体呈波动下降趋势,近年稍有回升。Joann E Manson是发文量和中介中心性最高的作者;弗雷德·哈钦森癌症研究中心是发文量最高且中介中心性最大的机构;美国、英国、意大利和中国是该领域论文高产出国家。共现频次排名前五的关键词包括风险、雌激素联合孕激素、心血管事件、冠心病和替代疗法;中介中心性>0.2的关键词包括成人、疾病、血压、动脉粥样硬化和流行。关键词数量≥10个的有效聚类为14个,分别是:#0乳腺癌、#1脂蛋白、#2心肌梗死、#3心血管事件、#4生活方式、#5症状、#6风险因素、#7风险、#8脂质、#9女性、#10 IGF-β受体、#11 VCAM-1、#12 C反应蛋白及#13 Ca^(2+)供应。暴发词检测中出现时间较早且突现强度较高的关键词为动脉粥样硬化和激素替代疗法。2000~2009年高频出现的关键词是激素替代疗法、血压、急性心肌梗死、危险因素及死亡率等,2010年及以后则主要集中于临床表现、流行资料、老年患者、欧洲国家、美国社会、标志物、生活方式和管理等。结论国际上,绝经后冠心病治疗的研究热点主要集中在药物口服辅以生活方式指导、运动训练等。其中,雌激素替代疗法成为主流。但该领域研究数量偏少,尚有较大的研究空间。OBJECTIVE To explore the hot topics and development trends of research related to the treatment of postmenopausal coronary heart disease(CHD)in the Core collection database of Web of Science(WoS)past 20 years using bibliometrics and provide reference for further research in this field.METHODS Taken WoS database as literature resource,all relative English literatures related to the treatment of postmenopausal CHD published on WoS in the last 20 years were retrieved.Citespace software was used to visualize the number of papers,network analysis,co-occurrence analysis and co-citation analysis.RESULTS A total of 1617 literatures were retrieved,and 329 literatures were finally included according to the exclusion criteria.The number of articles published in English in this field shows a trend of fluctuation and decline,and has picked up slightly in recent years.Joann E Manson was the author with the highest publication volume and mediating centrality.Fred Hutchinson Cancer Research Center was the most prolific and mediating center.The US,UK,Italy,and China were among the most prolific producers in this field.The top five keywords sorted by frequency of co-occurrence included risk,estrogen combined with progesterone,cardiovascular events,CHD,and replacement therapy.The key words of between centrality>0.1 included adult,disease,blood pressure,atherosclerosis and prevalence.There were 14 effective clustering tags with the number of keywords≥10,which were:#0 breast cancer risk,#1 lipoproteins,#2 myocardial infarction,#3 cardiovascular event,#4 diet,#5 symptom,#6 risk factor,#7 risk,#8 lipids,#9 women,#10 IGF-βreceptor,#11 VCAM-1,#12 C-reactive protein,#13 calcium supplementation.Atherosclerosis and hormone replacement therapy were the key words that appeared earlier and had higher burst intensity in the detection of burst words.From 2004 to 2009,the high frequency keywords were hormone replacement therapy,blood pressure,acute myocardial infarction,risk factors,mortality,etc.,and from 2010 onwards,they mainly focused on c
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