野生与栽培竹节参地下不同部位的质量比较  

Quality Analysis on Roots and Rhizomes of Wild and Cultivated Panax japonicus

作　　者：叶陈辉 唐海明 黄玲[1,2] 袁成福 张继红 袁丁[1,2,4] 何毓敏 YE Chen-hui;TANG Hai-ming;HUANG Ling;YUAN Cheng-fu;ZHANG Ji-hong;YUAN Ding;HE Yu-mina(Third-Grade Pharmacological Laboratory on Traditional Chinese Medicine,State Administration of Traditional Chinese Medicine,China Three Gorges University,Yichang 443002,China;College of Medicine and Health Science,China Three Gorges University,Yichang 443002,China;College of Basic Medical Sciences,China Three Gorges University,Yichang 443002,China;Hubei Heng′an Fulin Pharmaceutical Industry Group Co.,Ltd.,Yichang 443199,China;Hubei Clinical Research Center for Functional Digestive Diseases of Traditional Chinese Medicine,Yichang 443199,China)

机构地区：[1]三峡大学国家中医药管理药理科研三级实验室,湖北宜昌443002 [2]三峡大学健康医学院,湖北宜昌443002 [3]三峡大学基础医学院,湖北宜昌443002 [4]湖北恒安芙林药业股份有限公司,湖北宜昌443199 [5]湖北省功能性消化系统疾病中医临床医学研究中心,湖北宜昌443199

出　　处：《中国药学杂志》2023年第10期925-932,共8页Chinese Pharmaceutical Journal

基　　金：湖北省自然科学基金创新群体项目资助(2021CFA015);中央引导地方科技发展专项资金项目资助(2020ZYYD016);三峡大学青年科学基金资助(KJ2008A042)。

摘　　要：目的研究野生及栽培竹节参地下不同部位的质量差异,为竹节参药材质量标准的修订提供科学依据。方法采集28批不同产地的竹节参(含野生及栽培品)根状茎与肉质根,采用性状观察、中药指纹图谱、主要有效成分含量和浸出物测定等方法进行对比研究。结果野生与栽培竹节参地下部位的外观性状存在差异。15批样品中人参皂苷Ro和竹节参皂苷Ⅳa含量符合2020年版《中国药典》规定,合格率53.6%。合格批次野生和栽培竹节参根茎与根的化学指纹图谱、浸出物和有效成分含量差异不明显。结论本研究可为竹节参栽培品替代野生品使用,并为其质量标准“来源”“含量测定”“浸出物”等项目修订,以及后续竹节参资源研究开发提供科学依据。OBJECTIVE To explore the quality differences between roots and rhizomes of wild and cultivated Panax japonicus(P.japonicus),and to provide scientific evidence for the revision of P.japonicus quality standards.METHODS Twenty-one cultivated and 7 wild samples of root and rhizome of P.japonicus were collected.The difference as a measure of quality on morphological characteristics,alcohol extracts,HPLC fingerprints,and contents of ginsenoside Ro,chikusetsusaponinⅣandⅣa as the three most prominent saponins in roots and rhizomes of wild and cultivated P.japonicus,were comparatively analyzed.RESULTS There were some differences between the wild and the cultivated P.japonicus in the morphological characteristics.Otherwise,there were no significant differences between rhizomes and roots on chemical fingerprints,alcohol extracts and contents of the three most prominent saponins in 15 samples with qualified contents of ginsenoside Ro and chikusetsusapoin IVa according to the prescription of the Chinese Pharmacopoeia(2020 Edition).CONCLUSION The present study provids scientific evidences for the quality study on roots and rhizomes of wild and cultivated P.japonicus.

关 键 词：竹节参 野生 栽培 根茎 根 质量标准 皂苷类 

分 类 号：R282[医药卫生—中药学] R932[医药卫生—中医学]