基于文献的中药复方治疗儿童慢性扁桃体炎的用药规律研究  

Study on the Medication Rules of Traditional Chinese Medicine Compounds in the Treatment of Chronic Tonsillitis in Children Based on Data Mining

作　　者：普芳 周珊 张值伟 赵兰 唐彦 PU Fang;ZHOU Shan;ZHANG Zhiwei;ZHAO Lan;TANG Yan(The First Clinical Medical College of Yunnan University of Traditional Chinese Medicine,Kunming 650051,China)

机构地区：[1]云南中医药大学第一临床医学院,云南昆明650051

出　　处：《中国民族民间医药》2023年第13期114-118,共5页Chinese Journal of Ethnomedicine and Ethnopharmacy

摘　　要：目的:基于古今医案云平台分析中药治疗儿童慢性扁桃体炎的用药规律。方法:检索中国期刊全文数据库(CNKI)、中文科技期刊数据库(维普网)、中国学术期刊数据库(万方数据库)中治疗儿童慢性扁桃体炎的处方,建立数据库并录入古今医案云平台,进行药物频次分析、性味归经功效频次分析、关联规则分析和聚类分析。结果:共纳入40个处方,所涉中药68味,总频次117次,其中使用频次≥10次的有12味药,依次是甘草、玄参、桔梗、黄芩、浙贝母、连翘、金银花、夏枯草、生地黄、僵蚕、白术、黄芪,以寒性药物运用最多;药味以苦、甘、辛为多;药物多归肺经;以清热解毒药使用频次最多;得到10个常用药物组合及4个新方。结论:通过对中药复方治疗儿童慢性扁桃体炎的用药规律进行分析发现,本病的病机特点是余热邪气未清,久滞喉核,以余邪留恋、痰浊停滞、气阴两伤证多见,治疗宜标本兼治,以清利咽喉,化痰散结治其标,辅之以清热解毒,根据辨证以滋阴降火,健脾益气治其本。Objective To analyze the medication rule of traditional Chinese herbal compound in the treatment of Chronic Tonsillitis in Children based on the Ancient and Modern Medical Record Cloud Platform.Methods The prescriptions for the treatment of Chronic Tonsillitis in Children were retrieved from CNKI,VIP and Wanfang,and the database was established and entered into the Ancient and Modern Medical Record Cloud Platform.The frequencies of medicine,frequency analysis of properties,medicinal flavor and efficacy,the association rule analysis and the cluster analysis were carried out.Results A total of 40 prescriptions were included,involving 68 traditional Chinese medicines,with a total frequency of 117 times.Among them,12 medicines were used more than 10 times,followed by Glycyrrhiza uralensis,Radix Scrophulariae,Platycodon grandiflorum,Scutellaria baicalensis,Fritillaria thunbergii,forsythia,honeysuckle,Prunella vulgaris,Rehmannia glutinosa,Bombyx mori,Atractylodes macrocephala and Astragalus membranaceus.With the most use of cold medicines;The medicinal taste was mostly bitter,sweet and spicy,Most of the medicines belong to the lung meridian;The most frequently used antipyretic and antidote medicines,Ten commonly used drug combinations and four new prescriptions were obtained.Conclusion Through the analysis of the medication rules of Chinese herbal compound in the treatment of Chronic Tonsillitis in Children,it is found that the pathogenesis of this disease is characterized by residual heat and evil Qi not being cleared,stagnated in the throat for a long time,and the retention of residual evil,stagnation of phlegm,and Qi and Yin injury.The treatment should treat symptoms and root causes in both,and the symptoms should be treated by relieving sore throat,eliminating phlegm and dispersing the knot,supplemented with heat-clearing and detoxifying.According to the syndrome differentiation,the disease should be treated by Nourishing Yin and reducing fire,strengthening the spleen and supplementing qi.

关 键 词：儿童慢性扁桃体炎 中药复方 用药规律 数据挖掘 

分 类 号：R766.18[医药卫生—耳鼻咽喉科]