铅暴露对665名铅作业工人血压的影响  

Effects of lead exposure on blood pressure in 665 lead workers

作　　者：鲁碧峰 殷文军 戴霞云 陈振龙 周胜兰 LU Bifeng;YIN Wenjun;DAI Xiayun;CHEN Zhenlong;ZHOU Shenglan(Wuhan Prevention and Treatment Center for Occupational Diseases,Wuhan,Hubei 430015,China)

机构地区：[1]湖北省武汉市职业病防治院,湖北武汉430015

出　　处：《公共卫生与预防医学》2023年第4期59-62,共4页Journal of Public Health and Preventive Medicine

基　　金：职业危害识别与控制湖北省重点实验室开放基金(OHIC2020Y07)。

摘　　要：目的探讨铅暴露对铅作业工人血压的影响。方法选取武汉市部分铅蓄电池企业665名铅作业工人作为此次铅暴露组,708名无铅暴露的普通工作人员作为对照组,测量两组人群的血压,测量铅暴露组的血铅浓度。采用独立样本t检验对两组人群血压进行比较,采用线性回归模型分析铅暴露组血铅浓度与血压的关系,采用logistic回归分析方法,分析铅暴露组患高血压风险与血铅浓度的相关性。结果铅暴露组收缩压、舒张压、脉搏均值明显高于对照组,差异有统计学意义(P<0.05),两组人群脉压差,差异无统计学意义(P>0.05)。线性回归分析发现,铅暴露组血铅浓度与收缩压、舒张压均存在显著关联,血铅浓度每增加1μg/L,铅作业工人收缩压升高0.011 mmHg、舒张压升高0.007 mmHg。logistic回归分析发现,铅暴露组男性患高血压的风险高于女性,年龄越大、血铅浓度越高,患高血压的风险越高。结论血铅浓度与铅作业工人收缩压、舒张压存在正相关关系,铅作业工人年龄越大、血铅浓度越高,患高血压的风险越高。Objective To investigate the effect of lead exposure on blood pressure of lead workers.Methods A total of 665 lead workers from some lead-acid battery enterprises in Wuhan were selected as the lead exposure group,and 708 ordinary workers without lead exposure were selected as the control group.The blood pressure in the workers of both groups was measured.The blood lead concentrations were measured in the lead-exposed group.The independent samples t-test was used to compare the blood pressure between the two groups.Linear regression model was used to analyze the relationship between the blood lead concentration and the blood pressure in the lead-exposed group.Logistic regression analysis was used to analyze the relationship between the risk of hypertension and blood lead concentration in lead-exposed group.Results The mean values of systolic blood pressure,diastolic blood pressure and pulse in the lead exposure group were significantly higher than those in the control group,and the difference was statistically significant(P<0.05).There was no significant difference in pulse pressure difference between the two groups(P>0.05).Linear regression analysis revealed that blood lead concentrations were significantly correlated with both systolic and diastolic blood pressure in the lead exposure group.For each increase of 1μg/L of blood lead concentration in the lead exposure group,the systolic blood pressure of lead workers increased by 0.011 mmHg,and the diastolic blood pressure increased by 0.007 mmHg.Logistic regression analysis found that men in the lead-exposed group had a higher risk of hypertension than women.The older the age and the higher the blood lead concentration,the higher the risk of development of hypertension.Conclusion There is a positive correlation between the blood lead concentration and the systolic and diastolic blood pressure in lead workers.The older the lead workers,the higher the risk of developing high blood pressure.The higher the lead concentration in lead workers,the higher the risk of dev

关 键 词：铅作业工人 铅暴露 血压 

分 类 号：R135[医药卫生—劳动卫生]