氯霉素的毒性作用及检测方法研究进展  

Research Progress on the Toxic Effects and Detection Methods of Chloramphenicol

作　　者：杜春艳 吴发旺 Du Chun-yan;Wu Fa-wang

机构地区：[1]毕节医学高等专科学校,贵州毕节551700 [2]毕节市疾病预防控制中心,贵州毕节551700

出　　处：《化工设计通讯》2023年第7期81-83,共3页Chemical Engineering Design Communications

基　　金：2021年毕节市科学技术局毕节医学高等专科学校科学技术联合基金项目(毕科联合字yz〔2021〕4号)。

摘　　要：氯霉素(CAP)在一段时间内,曾作为广谱抗生素广泛应用于养殖业,后由于其毒副作用,在中国、美国、欧盟等多个国家和地区的相关检测标准中,均已规定动物性食品中不得检出氯霉素。氯霉素在我国,被要求禁止应用于动物性食品,但依旧存在违法滥用现象,造成氯霉素残留。因此,对常见的氯霉素检测方法进行对比,包括常见的色谱法、免疫法、化学发光法等多种方法,分析了各种方法的优劣势。Chloramphenicol(CAP)was widely used as a broad-spectrum antibiotic in the aquaculture industry for a period of time.However,due to its toxic side effects,it has been stipulated in the relevant testing standards of multiple countries and regions such as China,the United States,and the European Union that chloramphenicol should not be detected in animal food.Chloramphenicol is required to be prohibited from being used in animal foods in China,but there is still illegal abuse,resulting in residual chloramphenicol.In this article,the author compares common chloramphenicol detection methods,including chromatography,immunoassay,chemiluminescence,and other methods,and analyzes the advantages and disadvantages of each method.

关 键 词：氯霉素 毒性作用 检测方法 

分 类 号：TS254.7[轻工技术与工程—水产品加工及贮藏工程]