创伤后感染/脓毒症预防值得注意的几个问题  

Key issues on post-traumatic infection/sepsis prevention

作　　者：朱俊宇 梁华平 Zhu Junyu;Liang Huaping(State Key Laboratory of Trauma,Burns and Combined Injury,Department of Wound Infection and Drug,Daping Hospital,Army Medical University,Chongqing 400042,China)

机构地区：[1]陆军军医大学大坪医院战伤感染与特需药品研究室,创伤、烧伤与复合伤国家重点实验室,重庆400042

出　　处：《创伤外科杂志》2023年第7期485-490,共6页Journal of Traumatic Surgery

基　　金：国家自然科学基金(82202422,82072227);科技基础加强项目(2021-JCJQ-JJ-1081);重庆市自然科学基金面上项目(cstc2021jcyj-msxmX0234);重庆英才项目(2020CQYC01);重庆市博士直通车科研项目(CSTB2022BSXM-JCX0009);海南省临床医学研究中心项目(LCYX202205)。

摘　　要：感染/脓毒症是创伤患者常见的并发症及主要死亡原因。目前,预防创伤感染/脓毒症研究领域存在诸多难题,笔者重点围绕创伤后早期外科处理(清创、缝合、引流)、抗生素应用、感染疫苗、免疫调节剂选择及感染耐受调节剂研发五个方面进行阐述,为最大限度降低创伤患者感染及脓毒症发病率提供参考。Infection/sepsis is a common complication and main cause of death following trauma.At present,there are many difficulties in the field of traumatic infection/sepsis prevention.The authors focus on the following five aspects:early post-traumatic surgical management(debridement,suture,drainage),use of antibiotics,vaccine,choice of immunomodulators,and exploration foRinfection tolerance regulators,in ordeRto provide guidance foRminimizing the incidence of infection and sepsis in trauma patients.

关 键 词：创伤 感染 脓毒症 预防 

分 类 号：R641[医药卫生—外科学] R631.2[医药卫生—临床医学]