犬肠道淋巴管扩张症的临床诊治及预后分析  

Clinical Diagnosis,Treatment and Prognosis of Intestinal Lymphadenopathy in Canine

作　　者：马天文 王英雪 王明河 迟新宇 王姝 高利[1] 魏成威[1,2] MA Tianwen;WANG Yingxue;WANG Minghe;CHI Xinyu;WANG Shu;GAO Li;WEI Chengwei(College of Veterinary Medicine,Northeast Agricultural University,Heilongjiang Provincial Key Laboratory of Pathogenesis and Comparative Medicine of Animal Diseases,Harbin 150030,China;Heilongjiang Northeast Agricultural University Animal Clinical Teaching Hospital,Harbin 150030,China)

机构地区：[1]东北农业大学动物医学学院,黑龙江省动物疾病致病机制与比较医学重点实验室,哈尔滨150030 [2]黑龙江东北农大动物临床教学医院,哈尔滨150030

出　　处：《畜牧兽医学报》2023年第7期3102-3107,共6页ACTA VETERINARIA ET ZOOTECHNICA SINICA

摘　　要：犬肠道淋巴管扩张症(intestinal lymphangiectasia)是一种少见的蛋白丢失性肠病(protein-losing enteropathy,PLE),在兽医临床上非常罕见。在本报告中,描述了1例8岁雌性泰迪犬,其临床症状表现食欲下降,偶尔呕吐,持续性腹泻,被毛粗乱,腹部膨大和气喘等。超声检查发现,病犬空肠肠壁分层清晰,黏膜层中度增厚,黏膜层内回声增强,边界不清,可见非均匀分布的亮斑结构,腹腔后部少量腹水。结合该犬病史调查、临床症状、血液学检查及影像学检查等结果综合分析,诊断为犬肠道淋巴管扩张症。采取常规对症治疗性措施基础上,根据实际预后情况制定改善性食谱与药物相结合的治疗方案。经过两年多的长期维持治疗和预后随访,该犬体重明显增加,生化指标参数正常,B超影像学检查肠道症状明显好转。国内首次报道了犬肠道淋巴管扩张症临床病例及治疗方案,对于兽医临床上相关疾病的诊治和研究具有参考价值和借鉴意义。Canine intestinal lymphadenopathy is a rare protein-losing enteropathy that is very rare in veterinary practice.In this report,a case of an 8-year-old female Teddy is described with clinical signs of decreased appetite,occasional vomiting,persistent diarrhea,coarse and disheveled coat,abdominal enlargement and panting.Ultrasonographic examination revealed a well-defined stratification of the jejunal wall,moderate thickening of the mucosal layer,echogenic enhancement within the mucosal layer with unclear borders,non-uniformly distributed bright spot structures,and a small amount of ascites in the posterior part of the abdominal cavity.The dog was diagnosed with canine intestinal lymphadenopathy based on a comprehensive analysis of its medical history,clinical signs,hematological examination and imaging findings.Based on the conventional symptomatic therapeutic measures,a combination of improved recipes and medication was developed according to the actual prognosis.After more than two years of long-term maintenance treatment and prognostic follow-up,the dog showed significant weight gain,normalization of biochemical parameters,and significant improvement of intestinal symptoms on ultrasound imaging.This is the first report of a clinical case and treatment plan for canine intestinal lymphatic duct dilatation in China,which has reference value and significance for the diagnosis,treatment and research of related diseases in veterinary clinic.

关 键 词：肠道淋巴管扩张症 蛋白丢失性肠病 犬 临床诊治 

分 类 号：S854.5[农业科学—临床兽医学]