经尿道手术治疗良性前列腺增生预后影响因素的Meta分析  

Prognostic factors in patients with benign prostatic hyperplasia treated by transurethral sur-gery:a Meta-analysis

作　　者：黄荣木 庄惠强 沈春兰 陈佳海[3] 张少波[1] 张剑平 林荣凯 Huang Rongmu;Zhuang Huiqiang;Shen Chunlan;Chen Jiahai;Zhang Shaobo;Zhang Jianping;Lin Rongkai(Department of Urology,910th Hospital of PLA,Quanzhou 362000,China;Department of Neurology,910th Hospital of PLA,Quanzhou 362000,China;Department of Oncology,910th Hospital of PLA,Quanzhou 362000,China)

机构地区：[1]中国人民解放军联勤保障部队第910医院泌尿外科,泉州362000 [2]中国人民解放军联勤保障部队第910医院神经内科,泉州362000 [3]中国人民解放军联勤保障部队第910医院肿瘤内科,泉州362000

出　　处：《国际泌尿系统杂志》2023年第4期581-586,共6页International Journal of Urology and Nephrology

基　　金：泉州市科技计划项目(2015Z36)。

摘　　要：目的探讨经尿道手术治疗良性前列腺增生(BPH)的预后影响因素。方法系统检索中国知网、中国生物医学文献数据库、万方数据库、维普数据库、PubMed、Cochrane Library、Embase、Web of Science的文献,纳入1990年1月1日至2021年1月25日期间经尿道手术治疗BPH预后影响因素的队列研究或病例对照研究,依据纽卡斯尔-渥太华评分量表(NOS)进行文献质量评价,采用Review Manager 5.3软件进行Meta分析。结果共纳入13篇文献,包括4739例患者,分析结果显示:术前高膀胱内前列腺突入度(IPP)(OR=2.25,95%CI:1.20~4.21,P=0.010)、高储尿期症状评分(OR=0.92,95%CI:0.87~0.96,P<0.001)、高龄(OR=0.78,95%CI:0.64~0.97,P=0.020)、合并糖尿病(OR=0.43,95%CI:0.24~0.76,P=0.004)是影响经尿道手术治疗BPH患者的重要因素。结论术前高储尿期症状评分、高龄、合并糖尿病是经尿道手术治疗BPH术后症状无改善的危险因素,而高IPP是术后症状改善的保护因素。Objective To systematic evaluation the prognosis factors in patients with benign prostatic hyperplasia(BPH)treated by transurethral surgery.Methods Literatures from CNKI,China Biomedical Literature Database,Wanfang Database,VIP database,PubMed,Cochrane Library,Embase and Web of Science were systematically searched.A cohort study or case-control study on prognostic factors of transurethral surgery for BPH from January 1,1990 to January 25,2021 was included,and literature quality was evaluated according to Newcastle-Ottawa Scale.Meta analysis was performed using Review Manager 5.3 software.Results A total of 13 literatures were included,including 4739 patients.The analysis results showed that:preoperative high intracarical prostatic penetration(IPP)(OR=2.25,95%CI:1.20-4.21,P=0.010),high urinary storage symptom score(OR=0.92,95%CI:0.87-0.96,P<0.001),advanced age(OR=0.78,95%CI:0.64-0.97,P=0.020)and diabetes mellitus(OR=0.43,95%CI:0.24-0.76,P=0.004)were important factors affecting patients with BPH treated by transurethral surgery.Conclusions Preoperative high urinary storage symptom score,advanced age and diabetes mellitus were risk factors for no improvement of symptoms after transurethral surgery for BPH,and high IPP was protective factor for improvement of symptoms after surgery.

关 键 词：前列腺增生 经尿道前列腺切除术 尿动力学 

分 类 号：R699.8[医药卫生—泌尿科学]