麻杏苇茎汤加减治疗痰热瘀阻型支原体肺炎临床研究  

Clinical Study on the Treatment of Mycoplasma Pneumonia of Phlegm-Heat-Stasis Obstruction Type with Modified Ephedra and Apricot Kernel and Rhizoma Phragmitis Decoction

作　　者：栾大丽 LUAN Dali(Nanyang Second General Hospital,Nanyang,Henan,China,473012)

机构地区：[1]南阳市第二人民医院,河南南阳473012

出　　处：《河南中医》2023年第8期1198-1202,共5页Henan Traditional Chinese Medicine

摘　　要：目的:观察麻杏苇茎汤加减治疗痰热瘀阻型支原体肺炎的临床疗效。方法:选择108例痰热瘀阻型支原体肺炎患儿为研究对象,按照随机数字表法分为常规组50例和观察组58例。常规组给予阿奇霉素干混悬剂口服,观察组在常规组治疗的基础上给予麻杏苇茎汤加减。比较两组患儿的临床疗效、临床症状改善情况和不良反应发生率;检测两组患儿治疗前后白细胞计数(white blood cell,WBC)、C反应蛋白(C-reactive protein,CRP)、血沉、白细胞介素-6(interleukin-6,IL-6)、CD3^(+)、CD4^(+)及CD8^(+)等。结果:观察组有效率为91.38%,常规组有效率为78.00%,两组患儿有效率比较,差异具有统计学意义(P<0.05)。观察组体温恢复正常时间、咳嗽消失时间、肺部啰音消失时间、胸片阴影吸收时间及住院天数短于常规组,差异具有统计学意义(P<0.05)。两组患儿治疗后WBC、CRP、ESR、IL-6低于本组治疗前,且治疗后观察组低于对照组,差异有统计学意义(P<0.05)。两组患儿治疗后CD3^(+)、CD4^(+)高于本组治疗前,CD8^(+)低于本组治疗前,且治疗后组间比较,差异有统计学意义(P<0.05)。常规组不良反应发生率高于对照组,差异有统计学意义(P<0.05)。结论:麻杏苇茎汤加减治疗痰热瘀阻型支原体肺炎,可改善患儿的临床症状,缩短病程,降低炎性因子及血沉水平,提高免疫功能。Objective:To observe the clinical efficacy of Modified Ephedra and Apricot Kernel and Rhizoma Phragmitis Decoction on mycoplasma pneumonia with phlegm-heat-stasis obstruction syndrome.Methods:A total of 108 children with mycoplasma pneumonia of phlegm-heat-stasis obstruction type were selected as the study subjects,and randomly divided into the routine group with 50 cases and the observation group with 58 cases respectively according to the random number table method.The routine group was given Azithromy-cin Dry Suspension,while the observation group was given Modified Ephedra and A pricot Kernel and Rhizoma Phragmitis Decoction on the basis of the routine group.The clinical efficacy,improvement of clinical symptoms,and incidence of adverse reactions of the two groups were compared.White blood cell(WBC),C-reactive protein(CRP),erythrocyte sedimentation rate|(ESR),interleukin-6(IL-6),CD3^(+),CD4^(+)and CD8^(+)of the two groups were measured before and after treatment.Results:The effective rate of the observation group was 91.38%,while that of the routine group was 78.00%.The difference between the two groups was statistically significant(P<0.05).The observation group had a shorter time for body temperature to return to normal,cough to disappear,lung rales to disap-pear,film absorption time,and hospitalization time compared to the conventional group,and all the differences were statistically signifi-cant(P<0.05).After treatment,the W BC,CRP,ESR,and IL-6 of the two groups were lower than those of the same group before treat-ment,and the observation group's above indexes were lower than those of the control group,and all the differences were statistically sig-nificant(P<0.05);The levels of CD3^(+)and CD4^(+)in the two groups were higher than those of the same group before treatment,while 1198 the level of CD8^(+)was lower than that of the same group before treatment,and all the differences were statistically significant(P<0.05);The incidence of adverse reactions in the routine group was higher than that in the contro

关 键 词：支原体肺炎 儿童 痰热瘀阻证 麻杏苇茎汤 阿奇霉素干混悬剂 中西医结合疗法 

分 类 号：R259.631.2[医药卫生—中西医结合]