中西医治疗功能性消化不良研究进展  

Research Progress in the Treatment of Functional Dyspepsia with Traditional Chinese and Western Medicine

作　　者：陈玥[1,2] 屠庆祝 CHEN Yue;TU Qingzhu(Shandong University of Traditional Chinese Medicine,Jinan,Shandong,China,250000;Tai′an Hospital of Traditional Chinese Medicine,Tai′an,Shandong,China,271000)

机构地区：[1]山东中医药大学,山东济南250000 [2]泰安市中医医院,山东泰安271000

出　　处：《河南中医》2023年第8期1272-1279,共8页Henan Traditional Chinese Medicine

基　　金：山东省中医药科技项目(2021M068)。

摘　　要：西医认为,功能性消化不良(functional dyspepsia, FD)的发病机制主要与胃肠运动功能障碍、内脏高敏、幽门螺杆菌感染、胃酸分泌、十二指肠低度炎症、精神心理因素、脑肠轴、肠道菌群等有关,治疗包括一般治疗和药物治疗;中医认为,FD的主要病机以脾虚为本,气滞、血瘀、食积、痰湿等邪实为标,治疗主要包括中医内治法与中医外治法;中西医结合治疗FD能有效缓解临床症状,缩短治疗时间,减少不良反应的发生。目前,研究存在的问题是:(1)临床辨证分型及治疗方案不统一,缺乏客观性;(2)试验设计不严谨;(3)中医治疗多以临床观察为主,实验研究相对不足;(4)临床研究样本量较小。今后,应深入研究中西医结合治疗FD的作用机制,进行科学严谨的实验设计及客观合理大样本的随机对照临床试验研究,深化中西医之间的相互联系。According to Western medicine,the pathogenesis of functional dyspepsia(FD)is mainly related to gastrointestinal motor dys⁃function,visceral hypersensitivity,helicobacter pylori(Hp)infection,gastric acid secretion,low duodenal inflammation,psychopsycho⁃logical factors and cerebro⁃intestinal axis,intestinal flora,etc.The treatment includes general treatment and drug treatment.According to TCM,the main pathogenesis of FD is spleen deficiency as the root cause,qi stagnation,blood stasis,food accumulation,phlegm damp⁃ness and other pathogenic factors as the manifestations.The treatment mainly includes TCM internal treatment and TCM external treat⁃ment.The combination of traditional Chinese and Western medicine in the treatment of FD can effectively relieve clinical symptoms,shorten the treatment time and reduce the occurrence of adverse reactions.At present,the existing problems in the research are as fol⁃lows:(1)Clinical syndrome differentiation and treatment plan are not uniform,and lack of objectivity;(2)The experimental design is not rigorous;(3)TCM treatment is mainly based on clinical observation,and experimental research is relatively insufficient;(4)The sample size of clinical research is small.In the future,it is necessary to further study the mechanism of integrated Chinese and Western medicine in the treatment of FD,conduct scientific and rigorous experimental design,objective and reasonable randomized controlled clinical experiments with large samples,and deepen the interaction between Chinese and Western medicine.

关 键 词：功能性消化不良 中西医治疗 中医内治法 中医外治法 

分 类 号：R259[医药卫生—中西医结合]