中医药治疗骨关节炎研究进展  

Research Progress in the Treatment of Osteoarthritis with TCM

作　　者：涂荣丹 何婷 冷文飞 TU Rongdan;HE Ting;LENG Wenfei(Chongqing Medical University,Chongqing,China,400016;Traditional Chinese Medicine Hospital Dianjiang Chongqing Hospital Affiliated to Chongqing Medical University,Chongqing,China,408399)

机构地区：[1]重庆医科大学,重庆400016 [2]重庆医科大学附属垫江中医院,重庆408399

出　　处：《河南中医》2023年第8期1280-1286,共7页Henan Traditional Chinese Medicine

基　　金：重庆市卫生健康委员会中医药科研项目(2019ZY023377);重庆市卫生健康委员会中医痹病学重点学科建设项目[渝中医(2021)16号];垫江县科技项目(djkjxm2020shmskycxyw011)。

摘　　要：中医药治疗骨关节炎(osteoarthritis, OA)的方法包括中药内服、中药外用、针灸、推拿、针刀及穴位注射等。中医药运用不同的治疗方法,通过不同靶点与通路作用于OA,但回顾中医药治疗骨关节炎的相关进展,均倾向于临床疗效观察或实验研究,缺乏更多复合型研究,应结合临床研究、相关药理学研究以及实验验证,将现代病理学研究与中医病因病机结合互补,以更好地阐述中医药作用的机理。另外,中医药相关研究仍存在样本量较小,多为单中心研究等问题,且越来越多的研究涉及中医内治与外治相结合,或中西医联合治疗OA,缺乏多中心、大样本量研究,各个研究之间缺乏统一的治疗方案、观察指标以及预后评估,导致数据汇总或Meta分析时可纳入的标准研究证据不足。因此,中医药治疗OA需要更多的指南与专家共识支持,进一步规范中医治疗方案与疗效评估,使中医普遍、规范、系统地应用于OA的临床研究。The methods of TCM in treating osteoarthritis(OA)include Chinese medicinals for oral administration,Chinese medicinals for external application,acupuncture and moxibustion,massage,acupotomy,acupoint injection,etc.TCM uses different methods to act on OA through different targets and pathways.However,the review of relevant progress on OA treatment with TCM tends to be limited to clinical efficacy observation or experimental research,lacking more complex research.That′s why it is necessary to combine clinical re⁃search,relevant pharmacological research and laboratory verification,and connect modern pathology research with TCM etiology and pathogenesis to better explain the mechanism of TCM.In addition,TCM⁃related research still has problems such as small sample size,mostly single⁃center research.More and more research involves the combination of internal and external treatments of TCM,or the com⁃bined treatment of traditional Chinese and Western medicine for OA,and lacks multi⁃center and large sample size research,and unified treatment plan,observation indicators and prognosis assessment among various research.This results in insufficient evidence from stand⁃ard research that can be included in data aggregation or Meta⁃analysis.Therefore,TCM treatment of OA needs more guidelines and ex⁃pert consensus support,and it is necessary to further standardize TCM treatment plans and efficacy evaluation,so that TCM can be wide⁃ly standardized and systematically applied to OA clinical research.

关 键 词：骨关节炎 中药内服 中药外用 针灸疗法 推拿疗法 针刀疗法 穴位注射 

分 类 号：R274.9[医药卫生—中西医结合]