Biomedical applications of magnetosomes: State of the art and perspectives  

作　　者：Gang Ren Xia Zhou Ruimin Long Maobin Xie Ranjith Kumar Kankala Shibin Wang Yu Shrike Zhang Yuangang Liu 

机构地区：[1]Institute of Pharmaceutical Engineering,Huaqiao University,Xiamen,Fujian,361021,China [2]College of Materials Science and Engineering,Huaqiao University,Xiamen,Fujian,361021,China [3]College of Chemical Engineering,Huaqiao University,Xiamen,Fujian,361021,China [4]Division of Engineering in Medicine,Department of Medicine,Brigham and Women’s Hospital,Harvard Medical School,Cambridge,MA,02139,USA [5]The Sixth Affiliated Hospital of Guangzhou Medical University,Qingyuan People’s Hospital,School of Biomedical Engineering,Guangzhou Medical University,Guangzhou,511436,China [6]Fujian Provincial Key Laboratory of Biochemical Technology,Xiamen,Fujian,361021,China

出　　处：《Bioactive Materials》2023年第10期27-49,共23页生物活性材料（英文）

基　　金：support from the National Natural Science Foundation of China(32171337);the National Marine Economic Innovation and Development Project(16PYY007SF17).Thi。

摘　　要：Magnetosomes, synthesized by magnetotactic bacteria (MTB), have been used in nano- and biotechnological applications, owing to their unique properties such as superparamagnetism, uniform size distribution, excellent bioavailability, and easily modifiable functional groups. In this review, we first discuss the mechanisms of magnetosome formation and describe various modification methods. Subsequently, we focus on presenting the biomedical advancements of bacterial magnetosomes in biomedical imaging, drug delivery, anticancer therapy, biosensor. Finally, we discuss future applications and challenges. This review summarizes the application of magnetosomes in the biomedical field, highlighting the latest advancements and exploring the future development of magnetosomes.

关 键 词：MAGNETOSOME Bionic magnetosomes Magnetotactic bacteria Modification strategies Biomedical applications 

分 类 号：R318.08[医药卫生—生物医学工程]