蠕形螨与干眼的相关性研究  

Correlation between Demodex and dry eye disease

作　　者：曹丽媛 蒋鹏飞[1] 颜春薇 刘培 彭俊[2] 彭清华[1] CAO Liyuan;JIANG Pengfei;YAN Chunwei;LIU Pei;PENG Jun;PENG Qinghua(Hunan University of Chinese Medicine,Changsha,Hunan 410208,China;The First Hospital of HunanUniversity of Chinese Medicine,Changsha,Hunan 410007,China)

机构地区：[1]湖南中医药大学,湖南长沙410208 [2]湖南中医药大学第一附属医院,湖南长沙410007

出　　处：《湖南中医药大学学报》2023年第7期1325-1329,共5页Journal of Hunan University of Chinese Medicine

基　　金：国家自然科学基金面上项目(30772824,81574031);中医药防治五官科疾病湖南省重点实验室建设项目(2017TP1018);长沙市科技计划项目(K1501014-31,kc1704005);中央财政支持地方高校建设项目(2018—2019年);国家中医药管理局中医眼科学重点学科建设项目;湖南省中医五官科学重点学科建设项目;湖南省研究生科研创新项目(CX20220780);湖南中医药大学“一方”研究生创新项目(2022YF01)。

摘　　要：蠕形螨是人类常见的体表寄生虫之一,常因过度密集寄生体表而导致多种疾病产生。眼部蠕形螨感染症状多为睑板腺功能障碍、睑缘炎以及干眼等。干眼是一种常见的眼表炎症性疾病,影响全球数亿人。干眼病因较为复杂,近年研究报道表明其与蠕形螨感染关系密切。本文就蠕形螨与干眼的相关性研究进行理论探讨,旨在推动蠕形螨相关性干眼防控向纵深发展,减少蠕形螨对人体眼部的伤害,为干眼的临床诊治提供新的参考依据和新思路。Demodex is a common ectoparasite of human beings,and often causes a variety of diseases due to its high densities on the body surface.The symptoms of ocular Demodex infestation are mostly meibomian gland dysfunction,blepharitis,and dry eyes.Dry eye disease is a common ocular surface inflammatory disease that affects hundreds of millions of people worldwide.The causes of dry eye disease are complicated,and recent studies have shown that this disease is closely related to Demodex infestation.Through a theoretical discussion,this paper focuses on the correlation between Demodex and dry eye disease,aiming to promote the in-depth development of the prevention and control of Demodex-related dry eye disease,and reduce the damage of Demodex to human eyes,in the hope of providing a new reference and idea for clinical diagnosis and treatment of dry eye disease.

关 键 词：蠕形螨 干眼 理论探讨 中医药 眼表炎症 睑板腺功能障碍 机制分析 

分 类 号：R276.7[医药卫生—中医五官科学]