免疫功能失调与炎症反应相互作用加重围术期急性肺损伤  

Crosstalk between Immune Dysfunction and Inflammatory Response Exacerbates Perioperative Acute Lung Injury

作　　者：方兴君 曲良超[2] FANG Xing-jun;QU Liang-chao(Medical Department of Graduate School,the First Affiliated Hospital,Nanchang University,Nanchang 330006,China;Medical Center for Anesthesiology and Pain,the First Affiliated Hospital,Nanchang University,Nanchang 330006,China)

机构地区：[1]南昌大学研究生院医学部,南昌330006 [2]南昌大学第一附属医院麻醉与疼痛医学中心,南昌330006

出　　处：《实用临床医学（江西）》2023年第3期134-138,共5页Practical Clinical Medicine

摘　　要：围术期急性肺损伤(PALI)对手术患者临床结局具有显著的影响,因此积极预防和治疗PALI显得尤为重要.文章就免疫功能失调与炎症反应相互作用对PALI的影响进行综述,并进一步探讨了神经免疫抗炎通路—胆碱能抗炎通路对预防和治疗PALI的作用.Perioperative acute lung injury(PALI)has a significant impact on the clinical outcome of surgical patients.Therefore,it is particularly important to actively prevent and treat PALI.This paper reviews the influence of interaction between immune dysfunction and inflammatory response on PALI,and further explores the role of cholinergic anti-inflammatory pathway in the prevention and treatment of PALI.

关 键 词：围术期急性肺损伤 免疫功能 炎症反应 胆碱能抗炎通路 

分 类 号：R619[医药卫生—外科学]