鹿茸、三七等中药联合治疗骨质疏松症的临床疗效分析  

Clinical Efficacy Analysis of the Combined Treatment of Osteoporosis with Deer Antler and Panax Notoginseng and Other Traditional Chinese Medi⁃cines

作　　者：李小冬[1] 李海霞[2] 杨方军[1] 刘博 LI Xiaodong;LI Haixia;YANG Fangjun;LIU Bo(Department of Orthopedics and Traumatology,the Second Affiliated Hospital of Heilongjiang University of Traditional Chinese Medicine,Harbin,Heilongjiang Province,150001 China;CCU Ward,Heilongjiang Provincial Hospital,Harbin,Heilongjiang Province,150001 China;Graduate School of Heilongjiang University of Traditional Chinese Medicine,Harbin,Heilongjiang Province,150001 China)

机构地区：[1]黑龙江中医药大学附属第二医院骨伤科,黑龙江哈尔滨150001 [2]黑龙江省医院CCU病房,黑龙江哈尔滨150001 [3]黑龙江中医药大学研究生院,黑龙江哈尔滨150001

出　　处：《系统医学》2023年第7期26-29,53,共5页Systems Medicine

基　　金：黑龙江省中医药经典普及化专项课题项目(ZYW2022-009);黑龙江省中医药学会青年人才托举工程项目(2022-QNRC1-12)。

摘　　要：目的分析骨质疏松症治疗中,鹿茸、三七等中药联合治疗的应用价值。方法遵循随机对照原则,将2021年10月—2022年9月黑龙江中医药大学附属第二医院骨伤科80例骨质疏松症患者分为两组进行对比研究,选择其中40例实施仙灵骨葆治疗,设为对照组;剩余40例患者实施鹿茸、三七等中药联合治疗(中药汤剂),设为研究组。对两组患者的椎骨密度、尿钙/尿肌酐(U-Ca/Cr)比值、血清碱性磷酸酶(ALP)、血清钙(UCa)、功能障碍指数、疼痛评分、治疗总有效率进行统计学对比。结果研究组治疗后椎骨密度(0.83±0.05)g/cm^(2)高于对照组,差异有统计学意义(t=3.488,P<0.001);研究组疼痛评分(1.37±0.35)分、功能障碍指数(22.15±2.42)分低于对照组,差异有统计学意义(P<0.001);研究组ALP(94.56±10.24)IU/L、U-Ca/Cr(0.81±0.18)、UCa(2.23±0.14)mmol/L低于对照组,差异有统计学意义(P<0.05);研究组治疗总有效率(100.00%)高于对照组,差异有统计学意义(P<0.05)。结论鹿茸、三七等中药联合治疗后,对改善患者功能障碍、椎骨密度、血清碱性磷酸酶等指标状况具有积极意义,可以有效抑制疼痛指标,有效率较高。Objective To analyze the application value of the combination of traditional Chinese medicine such as deer antler and Panax notoginseng in the treatment of osteoporosis.Methods Following the principle of randomized control,80 patients with osteoporosis in the Department of Orthopaedic Injuries of the Second Affiliated Hospital of Heilongjiang University of Traditional Chinese Medicine were divided into two groups for comparative study from October 2021 to September 2022.Forty of these cases were selected to implement Xianling Gubao treatment,and was set as the control group.The remaining 40 patients were treated with a combination of Chinese herbal medicines such as deer antler and Panax notoginseng(Chinese herbal soup),and the group was named as the study group.The patients'vertebral bone density,urinary calcium/urinary creatinine(U-Ca/Cr)ratio,serum alkaline phosphatase(ALP),urinary calcium(UCa),dysfunction index,pain score,and total effective rate of treatment were statistically compared between the two groups.Results The vertebral bone density of the study group after treatment was(0.83±0.05)g/cm^(2)higher than that of the control group,and the difference was statistically significant(t=3.488,P<0.001).The pain score(1.37±0.35)points and dysfunction index(22.15±2.42)points of the study group were lower than those of the control group,and the difference was statistically significant(P<0.001).The ALP(94.56±10.24)IU/L,U-Ca/Cr(0.81±0.18)and UCa(2.23±0.14)mmol/L were lower than those in the control group,and the difference was statistically significant(P<0.05).The total effective rate of the study group(100.00%)was higher than that of the control group,and the difference was statistically significant(P<0.05).Conclusion After combined treatment with traditional Chinese medicine such as deer antler and Panax notoginseng,it has positive significance to improve the condition of patients'functional disorders,vertebral bone density,serum alkaline phosphatase and other indexes,and can effectively suppress pain index

关 键 词：骨质疏松症 鹿茸 三七 中药联合 椎骨密度 治疗有效率 

分 类 号：R59[医药卫生—内科学]