我国医务人员对芬太尼透皮贴剂治疗癌痛的临床应用和认知现状  

Investigation on the Chinese Medical Staff for the Clinical Application and Cognitive Status of Transdermal Fentanyl Patch in the Treatment of Cancer Pain

作　　者：王熙敏 李为 李敏[1] 尚天则 余早勤 张程亮 WANG Ximin;LI Wei;LI Min;SHANG Tianze;YU Zaoqin;ZHANG Chengliang(Department of Pharmacy,Tongji Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430030,China)

机构地区：[1]华中科技大学同济医学院附属同济医院药学部,武汉430030

出　　处：《医药导报》2023年第8期1248-1254,共7页Herald of Medicine

摘　　要：目的了解我国医务人员对芬太尼透皮贴剂的临床使用、认知现状及相关影响因素,为促进该药用于癌痛规范化治疗提供依据。方法采用整群抽样方法抽取全国癌痛治疗的医务人员500例,针对医务人员的基本情况、芬太尼透皮贴剂的临床使用情况、相关用药认知水平进行问卷调查,并运用卡方检验、二元Logistic回归法进行统计分析。结果共收到有效问卷500份,其中医师占80.8%;59.4%医务人员来自三甲医院。芬太尼透皮贴剂的使用量远低于羟考酮缓释片和吗啡缓释片,常用的规格为每贴4.125 mg。88.2%的调查对象接受了癌痛规范化治疗培训,但仅有56%的调查对象对芬太尼透皮贴剂相关知识的认知水平较高。工作年限、所在地区及是否经常使用癌痛评估工具与医务人员对芬太尼透皮贴剂相关知识的认知差异有统计学意义(P<0.01或P<0.05)。回归分析发现,医务人员所在的地区、是否经常使用癌痛评估工具是其对芬太尼透皮贴剂用药认知的影响因素。结论我国医务工作者对芬太尼透皮贴剂合理应用的水平仍有待提高,应加强教育及培训,尤其是在西部地区;需进一步推动癌痛规范化诊疗行为,提高芬太尼透皮贴剂在患者用药中的安全性和合理性。Objective To investigate the current status of clinical use and cognition of fentanyl transdermal patches among medical staff in China and the related influencing factors,and provide a basis for promoting the standardized treatment of cancer pain.Methods A total of 500 medical staff that deal with cancer pain in work were selected using whole group sampling method.A questionnaire survey was conducted on the basic information of medical staff,clinical use of fentanyl transdermal patch,and relevant cognition level about medication use,and chi-square test and binary logistic regression were used for statistical analysis.Results A total of 500 valid questionnaires were obtained,among which doctors accounted for the majority(80.8%),59.4% of the medical staff were from Grade-A tertiary hospitals.The dosage of fentanyl transdermal patches is much lower than that of oxycodone sustained-release tablets and morphine sustained-release tablets,and its common specification is 4.125 mg per patch.About 88.2%of the respondents had received training in the standardized treatment of cancer pain,but only 56% had a high level of cognition about the fentanyl transdermal patch.There were statistically significant differences in the knowledge of fentanyl transdermal patches among medical staff regarding working years,local area,and whether they often used cancer pain assessment tools(P<0.001 or P<0.05).Further regression analysis found that the region where medical staff worked and whether they often used cancer pain assessment tools influenced their cognition of fentanyl transdermal patch use.Conclusion The level of rational application of fentanyl transdermal patch in China still needs to be improved.Education and training in standardized treatment for cancer pain should be paid more attention,especially in Western China.The standardized diagnosis and treatment of cancer pain are worth further promotion,and medical staff need to develop awareness of pain assessment tools so that patients can get safer and more rational medication ins

关 键 词：芬太尼透皮贴剂 癌痛治疗 临床使用 医务人员 认知现状 

分 类 号：R969[医药卫生—药理学]