马来酸麦角新碱预防瘢痕子宫阴道分娩产后出血的临床效果  

Clinical effect of ergonovine maleate on prevention of postpartum hemorrhage after vaginal delivery with scar uterus

作　　者：邢佳玲 侯明敏[1] 贺丽荣[1] 周平[1] XING Jialing;HOU Mingmin;HE Lirong;ZHOU Ping(Women and Children's Hospital of Guangdong,Guangzhou 511442,China)

机构地区：[1]广东省妇幼保健院,广东广州511442

出　　处：《临床医药实践》2023年第8期579-582,共4页Proceeding of Clinical Medicine

摘　　要：目的:观察马来酸麦角新碱预防瘢痕子宫阴道分娩产后出血的安全性和有效性。方法:选取2019年3月—2020年9月瘢痕子宫阴道分娩的病例90例,随机分为对照组、观察A组和观察B组,分别采用缩宫素、缩宫素+卡前列素氨丁三醇、缩宫素+马来酸麦角新碱进行治疗,观察三组产后出血情况、血红蛋白下降情况及不良反应。结果:观察B组患者产后2 h,24 h出血量少于对照组和观察A组,差异有统计学意义(P<0.05);三组产妇的产后出血率及不良反应发生率比较差异无统计学意义。结论:瘢痕子宫阴道分娩后给予肌肉注射马来酸麦角新碱可有效减少产后出血量,预防产后出血的发生,且安全性较高。Objective:To observe the safety and effect of ergonovine maleate in preventing postpartum hemorrhage after vaginal delivery with scar uterus.Methods:A total of 90 cases with scar uterus after vaginal delivery were randomly divided into 3 groups,with 30 cases in each group.The control group received oxytocin injection,the observation group A received carboprost tromethamine combined with oxytocin injection,and the observation group B received ergonovine maleate combined with oxytocin injection.The amount of blood loss,occurrence of postpartum hemorrhage,hemoglobin decline and adverse reactions were compared between the three groups.Results:The amount of blood loss at 2 and 24 h postpartum of the observation group B were less than the control group and the observation group A.Both differences were statistically significant(P<0.05).There were no statistically significant differences in the occurrence of postpartum hemorrhage and adverse reactions among three groups.Conclusion:Ergonovine maleate injection after vaginal delivery with scar uterus can effectively reduce the amount of blood loss and prevent postpartum hemorrhage,with high safety.

关 键 词：瘢痕子宫 阴道分娩 产后出血 麦角新碱 

分 类 号：R711.52[医药卫生—妇产科学]