腹腔镜联合胆囊镜保胆取石术后应用消炎利胆片对胆囊结石合并胆总管结石患者的影响探讨  

Effect of Xiaoyan Lidan tablets on patients with cholecystolithiasis and choledocholithiasis after laparoscopic combined with choledochoscopic gallbladder-preserving cholelithotomy

作　　者：姚鑫 周博 YAO Xin;ZHOU Bo(Department of General Surgery,Liaocheng People's Hospital Dongchangfu Hospital,Liaocheng 252000,China)

机构地区：[1]聊城市人民医院东昌府院区普外科,252000

出　　处：《中国实用医药》2023年第13期104-107,共4页China Practical Medicine

摘　　要：目的 分析腹腔镜联合胆囊镜保胆取石术后应用消炎利胆片对胆囊结石合并胆总管结石的影响。方法 60例胆囊结石合并胆总管结石患者,均实施腹腔镜联合胆囊镜保胆取石术,以术后干预方法的不同分为对照组和观察组,每组30例。对照组术后采用常规护理,观察组术后在对照组基础上采用消炎利胆片治疗。比较两组患者消化不良、腹部胀痛消失时间及治疗后肝功能指标[血清谷草转氨酶(AST)、谷丙转氨酶(ALT)、γ-谷氨酰基转移酶(GGT)、碱性磷酸酶(ALP)]、肾功能指标(肌酐、尿素氮)水平。结果 观察组消化不良消失时间(5.05±0.75)d及腹部胀痛消失时间(4.16±0.57)d均短于对照组的(7.75±1.42)、(5.87±0.79)d,差异有统计学意义(P<0.05)。治疗后,观察组AST、ALT、GGT、ALP水平分别为(33.39±6.59)、(23.57±4.22)、(12.62±2.58)、(48.55±9.47)U/L,对照组分别为(31.64±6.41)、(22.48±4.19)、(11.81±2.45)、(49.62±9.78)U/L。治疗后,两组患者的AST、ALT、GGT、ALP水平比较,差异无统计学意义(P>0.05)。治疗后,观察组肌酐、尿素氮水平分别为(72.79±13.55)μmol/L、(3.77±0.36)mmol/L,对照组分别为(75.62±14.28)μmol/L、(3.68±0.31)mmol/L。治疗后,两组的肌酐、尿素氮水平比较,差异无统计学意义(P>0.05)。结论 胆囊结石合并胆总管结石患者在腹腔镜联合胆囊镜保胆取石术后使用消炎利胆片可以有效加快病情恢复,临床效果明显,值得广泛使用。Objective To analyze the effect of Xiaoyan Lidan tablets on patients with cholecystolithiasis and choledocholithiasis after laparoscopic combined with choledochoscopic gallbladder-preserving cholelithotomy.Methods A total of 60 patients with cholecystolithiasis and choledocholithiasis,all underwent laparoscopic combined with choledochoscopic gallbladder-preserving cholelithotomy,were divided into control group and observation group according to different postoperative intervention methods,with 30 cases in each group.The control group was treated with usual care after surgery,and the observation group was treated with Xiaoyan Lidan tablet after surgery on the basis of the control group.Both groups were compared in terms of disappearance time of dyspepsia,abdominal distension,liver function indexes[serum aspartate transaminase(AST),alanine aminotransferase(ALT),gamma-glutamyltransferase(GGT),alkaline phosphatase(ALP)]and renal function indexes(creatinine and urea nitrogen).Results The disappearance time of dyspepsia and abdominal distension were(5.05±0.75)and(4.16±0.57)d in the observation group,which were shorter than those of(7.75±1.42)and(5.87±0.79)d in the control group,and the differences were statistically significant(P<0.05).After treatment,the levels of AST,ALT,GGT and ALP were(33.39±6.59),(23.57±4.22),(12.62±2.58)and(48.55±9.47)U/L in the observation group,and(31.64±6.41),(22.48±4.19),(11.81±2.45)and(49.62±9.78)U/L in the control group.After treatment,there was no statistically significant difference in the levels of AST,ALT,GGT and ALP between the two groups(P>0.05).After treatment,the levels of creatinine and urea nitrogen of the observation group were(72.79±13.55)μmol/L and(3.77±0.36)mmol/L,while those of the control group were(75.62±14.28)μmol/L and(3.68±0.31)mmol/L.After treatment,there was no statistically significant difference in levels of creatinine and urea nitrogen between the two groups(P>0.05).Conclusion In patients with cholecystolithiasis and choledocholithiasis,the use of

关 键 词：胆囊结石 胆总管结石 腹腔镜联合胆囊镜保胆取石术 消炎利胆片 

分 类 号：R657.4[医药卫生—外科学]