“中药-头针-无错性学习”三联疗法治疗脑外伤后认知障碍临床研究  

Clinical study of triple therapy of“Chinese herb-scalp acupuncture-error free learning”on cognitive impairment after traumatic brain injury

作　　者：杨小燕 李德生 沈梅 YANG Xiaoyan;LI Desheng;SHEN Mei(Department of Rehabilitation Medicine,the People's Hospital of Longhua,Shenzhen,Shenzhen,Guangdong 518100)

机构地区：[1]广东省深圳市龙华区人民医院康复医学科,广东深圳518100

出　　处：《河北中医》2023年第7期1081-1084,共4页Hebei Journal of Traditional Chinese Medicine

基　　金：深圳市龙华区医疗卫生机构2020年区级科研项目(编号:2020074)。

摘　　要：目的观察“中药-头针-无错性学习”的三联疗法治疗脑外伤后认知障碍的临床疗效。方法选取80例脑外伤后认知障碍患者,按照随机数字表法分为4组,分别为对照组(n=20)、中药组(n=20)、头针组(n=20)和三联组(n=20)。4组均予常规内科药物及康复运动训练,对照组加无错性学习认知训练,中药组在对照组基础上加天麻配方颗粒治疗,头针组在对照组基础上加头针治疗,联合组在对照组基础上加天麻配方颗粒及头针治疗,共治疗8周。比较4组治疗前后蒙特利尔认知评估量表(MoCA)、简易智能精神状态检查量表(MMSE)和改良Barthel指数(MBI)评分。结果治疗后,4组MoCA、MMSE、MBI评分均较本组治疗前升高,且中药组、头针组及三联组均高于对照组,三联组高于中药组和头针组,比较差异均有统计学意义(P<0.05),中药组与头针组组间比较差异无统计学意义(P>0.05)。结论“中药-头针-无错性学习”的三联疗法可提高脑外伤后认知障碍患者的认知功能、日常生活活动能力,进而提高生活质量,疗效优于单纯头针、中药及认知训练治疗。Objective To investigate the clinical effect of"Chinese herb-scalp acupuncture–error free learning"triple therapy on cognitive impairment after traumatic brain injury(TBI).Methods Totally 80 TBI patients with cognitive impairment were randomized 1∶1∶1∶1 to group.Based on routine drugs and rehabilitation training,the patients received either error-free learning and cognitive training(control group),Tianma Granules+error-free learning and cognitive training(Chinese herb group),scalp acupuncture+error-free learning and cognitive training(scalp acupuncture group),or scalp acupuncture+Tianma Granules+error-free learning and cognitive training(triple group)for 8 weeks.The scores of Montreal Cognitive Assessment(MoCA),Mini-Mental State Examination(MMSE)and Modified Barthel Index(MBI)were included as comparisons among groups before and after treatment.Results After treatment,the scores of MoCA,MMSE and MBI in the four groups were significantly increased,which were significantly better in Chinese herb group,scalp acupuncture group and triple group than in the control group,and triple group had significantly better efficacy than Chinese herb group,scalp acupuncture group(P<0.05).There was no significant difference in the above indexes between Chinese herb group and scalp acupuncture group(P>0.05).Conclusion For patients with TBI,the triple therapy of"Chinese herb-scalp acupuncture–error free learning"can improve their cognitive function,daily living ability and quality of life.The triple curative effect is better than simple Chinese herb,scalp acupuncture or cognitive training.

关 键 词：脑损伤 创伤性 认知障碍 植物药疗法 头针疗法 无错性学习 

分 类 号：R651.150.5[医药卫生—外科学]