胰岛素泵强化治疗方案对控制初诊2型糖尿病患者下肢血管病变的效果探讨  

Exploring the Effect of Insulin Pump Intensive Treatment Program on Controlling Lower Extremity Vascular Lesions in Patients with Primary Diagnosis of Type 2 Diabetes Mellitus

作　　者：孙宇 SUN Yu(Department of General Internal Medicine,Jingjiang Hospital of Integrated Traditional Chinese and Western Medicine,Jingjiang,Jiangsu Province,214527 China)

机构地区：[1]靖江市中西医结合医院普内科,江苏靖江214527

出　　处：《糖尿病新世界》2023年第10期173-176,共4页Diabetes New World Magazine

摘　　要：目的观察胰岛素泵强化治疗方案对控制初诊2型糖尿病(type 2 diabetes mellitus,T2DM)患者下肢血管病变的临床效果。方法通过数字随机法抽取2021年1月—2022年6月期间靖江市中西医结合医院普内科收治的96例初诊2型糖尿病患者,将其中行常规血糖控制疗法的45例作为对照组,另将在对照组治疗基础上开展胰岛素泵强化治疗方案的51例作为研究组,对比两组治疗前后患者血糖水平和治疗疗效。结果治疗后,研究组FPG、2 hPG、HbA1c水平较对照组更低,HOMA-IR较对照组更高,差异有统计学意义(P<0.05);治疗后,研究组ABI、LEAD评分较对照组更高,差异有统计学意义(P<0.05);研究组总有效率显著高于对照组,差异有统计学意义(P<0.05);研究组低血糖发生率低于对照组,差异有统计学意义(P<0.05)。结论胰岛素泵强化治疗方案能够有效控制T2DM患者血糖水平,减缓下肢血管病变风险,值得推广。Objective To observe the clinical effect of insulin pump intensive treatment program on the control of lower extremity vascular lesions in patients with primary diagnosis of type 2 diabetes mellitus(T2DM).Methods Ninety-six patients with primary type 2 diabetes mellitus admitted to the Department of General Internal Medicine of Jingjiang Hospital of Integrated Traditional Chinese and Western Medicine from January 2021 to June 2022 were se-lected by digital randomization method.45 patients treated with conventional glycemic control therapy were assigned to the control group,and 51 patients treated with insulin pump intensive therapy based on the control group were as-signed to the study group.The blood glucose levels before and after treatment and treatment efficacy of the patients were compared between the two groups.Results After treatment,the levels of FPG,2 hPG,and HbA1c in the study group were lower than those in the control group,and HOMA-IR was higher than that in the control group,the differ-ence was statistically significant(P<0.05).The ABI and LEAD scores in the study group were higher compared with the control group after treatment,the difference was statistically significant(P<0.05).The total effective rate in the study group was significantly higher than that in the control group,the difference was statistically significant(P<0.05).The incidence of hypoglycemia in the study group was lower compared with the control group,the difference was statis-tically significant(P<0.05).Conclusion The insulin pump intensive treatment program can effectively control the blood glucose level of T2DM patients and slow down the risk of lower extremity vascular lesions,which is worth promoting.

关 键 词：胰岛素泵 强化治疗方案 控制 初诊2型糖尿病 下肢血管病变 

分 类 号：R587.1[医药卫生—内分泌]