放射性肠炎临床诊疗新进展  

Advances in clinical diagnosis and treatment of radiation enteritis

作　　者：马辰莺[1] 赵晶 徐晓婷[1] 秦颂兵[1] 周菊英[1,2] Ma Chenying;Zhao Jing;Xu Xiaoting;Qin Songbing;Zhou Juying(Department of Radiation Oncology,the First Affiliated Hospital of Soochow University,Suzhou 215006,China;State Key Laboratory of Radiation Medicine and Protection,Soochow University,Suzhou 215123,China)

机构地区：[1]苏州大学附属第一医院放疗科,苏州215006 [2]放射医学与辐射防护国家重点实验室(苏州大学),苏州215123

出　　处：《国际肿瘤学杂志》2023年第1期28-32,共5页Journal of International Oncology

基　　金：国家自然科学基金(81602792、81602802);苏州大学放射医学与辐射防护国家重点实验室资助项目(GZK1202101);苏州市科技发展计划(SS201628、KJXW2020008);苏州大学附属第一医院自然科学基金博习培育计划(BXQN202107)。

摘　　要：小肠胶囊内镜与双气囊小肠镜检查逐渐成为临床诊断放射性肠炎(RE)的新手段,尤其是对异常肠道组织的诊断。靶向活检或介入治疗有望实现RE的精准治疗。而筛选生物样本中的分子标志物也成为RE诊断新方向。粪便微生物群移植已成为具有前景的RE治疗手段之一,此外基于传统中草药、靶问细胞死亡以及组学分析的机制研究为RE的诊疗提供了新策略。Small bowel capsule endoscopy and double-balloon enteroscopy have become new methods for clinical diagnosis of radiation enteritis(RE),especially for abnormal intestinal tissue.Targeted biopsy or interventional therapy is expected to achieve precision treatment of RE.The screening of molecular markers in biological samples has also become a new direction for RE diagnosis.Fecal microbiota transplantation has become one of the promising treatments for RE.In addition,mechanism studies based on traditional Chinese medicine,targeted cell death,and omics analysis provide rich strategies for the diagnosis and treatment of RE.

关 键 词：盆腔肿瘤 胃肠疾病 放射性肠炎 

分 类 号：R818.8[医药卫生—放射医学]