综合评价法在中医药临床疗效评价中的应用  

Application of comprehensive evaluation methods in efficacy evaluation of traditional Chinese medicine

作　　者：胡晶[1] 张会娜[1] 王宏[1] 李博[1] HU Jing;ZHANG Hui-na;WANG Hong;LI Bo(Beijing Hospital of Traditional Chinese Medicine Afiliated to the Capital Medical University/Beijing Evidence-based Medicine Center of Traditional Chinese Medicine,Beijing Institute of Traditional Chinese Medicine,Beijing 100010,China)

机构地区：[1]首都医科大学附属北京中医医院北京市中医药研究所北京中医药循证医学中心,北京100010

出　　处：《北京中医药》2023年第5期482-486,共5页Beijing Journal of Traditional Chinese Medicine

基　　金：国家自然科学基金项目(81973694);北京市东城区优秀人才项目(2022-dchrcpyzz-56)。

摘　　要：临床疗效是中医药传承和发展的根本,而缺乏被中西医共同认可的疗效评价方法目前仍是一个亟待解决的问题。综合评价法是对一个复杂系统多个指标进行总评价的方法,其核心思想是根据不同的评价目的,利用被评价对象的各种属性信息,采用科学的评价方法对被评价对象进行客观、公正、合理的全面比较、判断及排序的过程,它可以将实验室指标、中医证候、生存质量等多个维度指标组合成一个单维度的综合指标,能够体现中医药多靶点、多维度的治疗优势,近年来已逐渐应用于中医药临床疗效评价。本文对目前中医药领域常用的几种综合评价法的原理、在中医药疗效评价应用的具体实例、以及注意事项进行介绍,以期指导中医药研究者正确选择和使用综合评价法,为全面客观地评价中医药临床真实疗效提供方法学支持。Clinical efficacy is the foundation of the inheritance and development of traditional Chinese medicine(TCM).The lack of efficacy evaluation methods recognized by both Chinese and western medicine is still an urgent issue to be solved.Comprehensive evaluation method is a kind of method for multiple indicators of a complex system.According to different evaluation purposes,it utilizes various attribute information of the evaluated object and use scientific evaluation methods to conduct an objective,fair and reasonable comprehensive comparison,judgment and sequencing process for the evaluated object.It can combine multiple dimensional outcomes such as western medicine-related outcomes,TCM-related syndromes,and quality of life into a single-dimensional comprehensive index,which can reflect the advantages of the multi-target and multi-dimensional efficacy of TCM,and has been gradually applied to the clinical efficacy of TCM in recent years.This article introduces the principles of several comprehensive evaluation methods commonly used in the field of traditional Chinese medicine,and specific examples of their application in the clinical efficacy evaluation of TCM and matters needing attention.We hope to help TCM researchers to correctly select and use comprehensive evaluation methods in order to provide methodological support for the comprehensive and objective evaluation of the true clinical efficacy of TCM.

关 键 词：综合评价法 随机对照试验 中医药 疗效评价 

分 类 号：R2-03[医药卫生—中医学]