Lawesson’s reagent-promoted deoxygenation of γ-hydroxylactams or succinimides for the syntheses of substituted pyrroles  

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作  者:Tao Shi Xiaodong Wang Gaofeng Yin Zhen Wang 

机构地区:[1]School of Pharmacy,Lanzhou University,No 199 West Donggang Road,Lanzhou,China [2]School of Pharmaceutical Science,Hengyang Medical School,University of South China,Hengyang 421001,Hunan,China

出  处:《Organic Chemistry Frontiers》2022年第6期1599-1603,共5页有机化学前沿(英文)

摘  要:A new method of Lawesson’s reagent-promoted deoxygenation of γ-hydroxypyrrolidones or succinimides was developed for synthesizing substituted pyrroles with 92 examples displayed. This reaction features simple operation, satisfactory yields, wide substrate scope, and excellent functional group tolerance.This robust protocol has been successfully applied in the expeditious syntheses of the key intermediate ofStemona alkaloids.

关 键 词:SUBSTITUTED REAGENT promoted 

分 类 号:O62[理学—有机化学]

 

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