Asymmetric synthesis of tricyclic 6,5,5-fusedpolycycles by the desymmetric Pauson–Khandreaction  

作　　者：Qi Teng Dong Chen Chen-Ho Tung Zhenghu Xu 

机构地区：[1]Key Lab of Colloid and Interface Chemistry of Ministry of Education,School of Chemistry and Chemical Engineering,Shandong University,No.27 South Shanda Road,Jinan,Shandong 250100,China [2]State Key Laboratory of Organometallic Chemistry Shanghai Institute of Organic Chemistry,Chinese Academy of Sciences,Shanghai 200032,PR China [3]Key Laboratory of Precise Synthesis of Functional Molecules of Zhejiang Province,School of Science,Westlake University,18 Shilongshan Road,Hangzhou 310024,Zhejiang Province,China

出　　处：《Organic Chemistry Frontiers》2022年第6期1680-1685,共6页有机化学前沿（英文）

基　　金：support from the Natural Science Foundation of China and Shandong Province(No.21971149,92156007,ZR2019ZD45,and ZR2020KB005);the Fundamental Research Funds of Shandong University.

摘　　要：A new rhodium(I)–BINAP-catalyzed enantioselective desymmetric Pauson–Khand (PK) reaction of prochiral 1,6-enynes with CO has been developed. Diverse tricyclic 6,5,5-fused bowl type polycycles withthree continuous chiral centers were synthesized in one step with a single diastereomer and extremelyhigh enantioselectivities.

关 键 词：FUSED symmetric CHIRAL 

分 类 号：O62[理学—有机化学]