基于科技文本挖掘的中医药干预水肿知识图谱分析  

Analysis on knowledge mapping of edema treated with TCM:a bibliometrics based quantitative study

作　　者：郑昊然 张并璇[2] 宋庆桥[2] 石树青 吴华芹[3] 李雨濛 徐霞 吕佳誉 王亚娇 毛信心 Zheng Haoran;Zhang Bingxuan;Song Qingqiao;Shi Shuqing;Wu Huaqin;Li Yumeng;Xu Xia;Lyu Jiayu;Wang Yajiao;Mao Xinxin(Beijing University of Chinese Medicine,Beijing 100029,China;General Department,Guang'anmen Hospitall,China Academy of Chinese Medical Sciences,Beijing 100053,China;Department of Cardiology,Guang'anmen Hospitall,China Academy of Chinese Medical Sciences,Beijing 100053,China;China Academy of Chinese)

机构地区：[1]北京中医药大学,北京100029 [2]中国中医科学院广安门医院综合科,北京100053 [3]中国中医科学院广安门医院心血管科,北京100053 [4]中国中医科学院广安门医院,北京100053

出　　处：《国际中医中药杂志》2023年第7期884-891,共8页International Journal of Traditional Chinese Medicine

基　　金：国家中医药管理局标准化项目(GZY-FJS-2020-214)。

摘　　要：目的应用文献计量学方法分析国内中医药干预水肿相关疾病的研究历程、热点及趋势,为中医水肿病证诊疗标准的修订提供参考。方法检索中国知识资源总库(CNKI)、中国学术期刊数据库(万方数据)、中文科技期刊数据库(重庆维普)、中国生物医学文献数据库(CBM)1995年1月1日-2022年5月25日中医药治疗水肿相关研究文献。采用CiteSpace、VOSviewer绘制知识图谱,分析机构、作者、关键词、热点机制的共现及聚类特征。结果纳入文献3198篇。年发文量总体呈螺旋上升趋势,发文量最多的机构是辽宁中医药大学;发文量最多的核心作者是孙伟(13篇);合作强度最高的是杨洪涛团队;关键词形成7个聚类,热点机制有代谢紊乱、免疫平衡、抗炎、钙磷代谢等。近7年突现关键词有“膜性肾病”“慢性心衰”“消渴”“糖尿病”“淋巴水肿”等。结论中医药干预水肿领域关注度总体呈上升趋势,近2年有所下降,研究类别集中在名医经验、临床试验、机制研究上,肾病相关水肿是一直以来的研究重点;DN、慢性心力衰竭、代谢组学、免疫治疗等有望成为下一阶段关注重点。Objective Applying bibliometrics to analyze the research history,hotspots and trends of Traditional Chinese Medicine(TCM)interventions in edema-related diseases,and to provide reference for the revision of diagnostic and therapeutic criteria for edema in TCM.Methods The literature about edema treated with TCM was retrieved from CNKI,Wanfang,VIP,CBM from 1st.Jan 1995 to 25th.May 2022.CiteSpace and VOSviewer softwares were used to draw the knowledge map,and analyze the co-occurrence relationship and clustering characteristics of the institution,author,keywords and mechanism hotspots.Results Totally 3198 articles were included.The annual number of documents issued generally shows a spiral rise trend.Liaoning University of Chinese Medicine published the most articles.Core authors published the most articles were Sun Wei(13 articles);the team with the highest cooperation intensity was Yang Hongtao's team;keywords formed 7 clusters.Hotspot mechanisms included metabolic disorders,immune balance,anti-inflammation,calcium and phosphorus metabolism.Keywords in the past 7 years were membranous nephropathy,chronic heart failure,diabetes,lymphedema etc.Conclusions The attention paid to the intervention of TCM in the field of edema is generally on the rise,and has decreased in the past two years.The research categories focus on the experience of famous doctors,clinical trials,and mechanistic studies,and nephropathy-related edema has been the focus of research;diabetic nephropathy,chronic heart failure,metabolomics,and immunotherapy are expected to be the focus of attention in the next stage.

关 键 词：中医药疗法 水肿 CiteSpace VOSviewer 数据可视化 文献计量学 

分 类 号：R259[医药卫生—中西医结合] G353.1[医药卫生—中医内科学]