空军青少年航空学校高三年级学生屈光状态与眼球生物学参数的相关性研究  

Correlation between refractive status and ocular biological parameters among students of grade three in teenagers aviation schools of Air Force

作　　者：齐林嵩 姚璐 王雪峰 刘勇 赵琎 吴腾云 赵晨 杨庆红 邹志康 QI Linsong;YAO Lu;WANG Xuefeng;LIU Yong;ZHAO Jin;WU Tengyun;ZHAO Chen;YANG Qinghong;ZOU Zhikang(Department of Ophthalmology,Air Force Medical Center,Beijing 100142,China;Pilot Selection Bureau of PLA Air Force,Beijing 100195,China;Department of Scientific Research Administration,Air Force Medical University,Xi'an 710032,China)

机构地区：[1]空军特色医学中心眼科,北京100142 [2]空军招飞局,北京100195 [3]空军军医大学科研学术处,陕西西安710032

出　　处：《空军军医大学学报》2023年第7期633-637,共5页Journal of Air Force Medical University

基　　金：国家自然科学基金(81800854);国防科技创新特区联合创新项目(20-163-15-ZT-001-001-01,20-163-15-ZT-001-001-08,20-163-15-ZT-001-001-10,224-CXCY-M113-07-01-01);空军军医大学效能提升项目(2021HKYX24)。

摘　　要：目的 分析空军青少年航空学校高三年级学生屈光状态与眼球生物学参数的相关性,探讨青少年航空学校学生近视防控的重点监测指标。方法 选取来自15个城市16所空军青少年航空学校的高三年级学生687人,均为男性,年龄17~19岁。通过睫状肌麻痹后的检影验光得到学生的等效球镜屈光度(SER),采用光学相干生物学测量仪测量学生的眼球生物学参数,包括眼轴(AL),平坦、陡峭角膜曲率(K1、K2),前房深度(ACD),晶体厚度(LT),角膜厚度(CCT),瞳孔大小(PS),角膜直径(WTW)。计算玻璃体腔长度(VCD),VCD=AL-ACD-CCT-LT。根据是否近视分为近视组(≤-0.50 D组)及非近视组。非近视组根据SER分为4个亚组,分别是>-0.50~0 D组、>0~+0.50 D组、>+0.50~+1.00 D组及>+1.00 D组。采用独立样本t检验比较近视组与非近视组SER和眼球生物学参数;采用单因素方差分析及Bonferroni矫正进行不同屈光亚组学生SER与眼球生物学参数的两两比较;采用Pearson相关性分析SER与眼球生物学参数的相关性,采用多因素回归分析得出SER与各生物学参数的回归方程。结果 (1)SER近视组学生显著低于非近视组学生(P<0.01),AL、ACD和VCD近视组学生显著高于非近视组学生,LT近视组学生显著低于非近视组学生(P<0.01);(2)≤-0.50 D组、>-0.50~0 D组、>0~+0.50 D组学生AL、VCD随SER降低而显著增长(P<0.01,P<0.05);≤-0.50 D组学生ACD较>0~+0.50 D、>+0.50~+1.00 D、>+1.00 D组学生ACD明显加深(P<0.01),>-0.50~0 D组学生ACD较>+0.50~+1.00 D、>+1.00 D组学生ACD明显加深(P<0.01);≤-0.50 D组学生LT明显薄于其他亚组学生LT(P<0.01),>-0.50~0 D、>0~+0.50 D、>+0.50~+1.00 D三组LT无显著差异(P>0.05),>+1.00 D组学生LT显著厚于其他亚组学生LT(P<0.01,P<0.05);(3)近视组学生SER与AL、LT、VCD存在低度相关,非近视组学生SER与AL、ACD、VCD、LT、PS存在低度相关;K1、K2、CCT、WTW与SER无显著相关性。结论 青少年航空学校学生的AL、AObjective To analyze the correlation between refractive status and ocular biological parameters among students of grade three in teenagers aviation schools of Air Force,and to explore the key monitoring indicators for myopia prevention and control of students in teenagers aviation schools of Air Force.Methods A total of 687 students of grade three from 16 teenagers aviation schools of Air Force in 15 cities were recruited,all male,aged 17-19 years old.The spherical equivalent refraction(SER)of the students was obtained by retinoscopy after cycloplegia.Ocular biological parameters were detected by an optical coherence biometry instrument,including axial length(AL),flat and steep corneal curvature(K1,K2),anterior chamber depth(ACD),lens thickness(LT),central corneal thickness(CCT),pupil size(PS),and white-to-white(WTW).Vitreous chamber depth(VCD)was calculated(VCD=AL-ACD-CCT-LT).Students were divided into myopic group(≤-0.50 D group)and non-myopic group according to whether they were myopic or not.The non-myopic group was divided into four subgroups according to the SER,namely>-0.50~0 D group,>0~+0.50 D group,>+0.50~+1.00 D group and>+1.00 D group.Independent sample t-test was used to compare SER and ocular biological parameters between myopic group and non-myopic group.One-way ANOVA and Bonferroni correction were used to compare SER and ocular biological parameters in students of different refractive subgroups.Pearson correlation analysis was used to analyze the correlation between SER and ocular biological parameters,and multivariate regression analysis was used to obtain the regression equation between SER and various ocular biological parameters.Results①The SER of myopic students was significantly lower than that of non-myopic students(P<0.01),the AL,ACD and VCD of myopic students were significantly higher than those of non-myopic students,and LT of myopic students was significantly lower than that of non-myopic students(P<0.01).②The AL and VCD were significantly increased with the decrease of SER in≤-0

关 键 词：眼轴 晶状体厚度 角膜曲率 眼球生物学参数 青少年航空学校 

分 类 号：R851.3[医药卫生—航空、航天与航海医学]