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作 者:吴夕霞 何玉腊 WU Xixia;HE Yula(Department of Cardiovascular Medicine,the First Affiliated Hospital of Air Force Military Medical University of Chinese People’s Liberation Army,Shaanxi Province,Xi’an710032,China)
机构地区:[1]空军军医大学第一附属医院心血管内科,陕西西安710032
出 处:《中国医药导报》2023年第21期159-162,共4页China Medical Herald
基 金:陕西省自然科学基础研究计划项目(2017JM 8132)。
摘 要:目的分析术后JBI规范化饮水指导对心血管介入术后患者肾功能保护的影响。方法在空军军医大学第一附属医院2019年1月至2021年1月接受心血管介入术的患者中,采取便利抽样法纳入98例进行研究,根据随机数字表法将其分为JBI组和对照组,各49例。术后JBI组实施基于JBI的饮水规范指导,对照组采用常规饮水规范指导。比较术后两组造影剂肾病(CIN)发生率及手术前后各项肾功能指标水平,同时统计并比较术后除CIN之外并发症的发生率。结果术后,JBI组CIN发生率低于对照组(P<0.05)。术后48 h,两组血清肌酐、肾小球滤过、肌酐清除率、血清尿酸、血清尿素氮水平均高于术前,但JBI组低于对照组(P<0.05)。JBI组术后并发症总发生率低于对照组(P<0.05)。结论在心血管介入术后为患者实施JBI规范化饮水指导,不仅可显著降低造影剂对肾功能的损伤,还可在一定程度上降低术后预后风险事件的发生率。Objective To analyze the effect of JBI standardized drinking water guidance on renal function protection in patients after cardiovascular intervention surgery.Methods In the First Affiliated Hospital of Air Force Military Medical University of Chinese People’s Liberation Army from January 2019 to January 2021,98 patients who received cardiovascular interventional surgery were included by convenience sampling method for study.According to random number table method,they were divided into JBI group and control group,with 49 cases in each group.After operation,JBI group was given the guidance of drinking water based on JBI,and control group was given the guidance of conventional drinking water standard.The incidence of contrast-induced nephropathy(CIN)and various renal function indexes before and after operation were compared between the two groups,and the incidence of postoperative complications except CIN was statistically compared.Results After operation,the incidence of CIN in the JBI group was lower than that in the control group(P<0.05);48 h after surgery,serum creatinine,glomerular filtration,creatinine clearance,serum uric acid and serum urea nitrogen levels in two groups were higher than those before surgery,but lower than those in JBI group(P<0.05).The incidence of postoperative complications in JBI group was lower than that in control group(P<0.05).Conclusion The implementation of JBI standardized drinking water guidance for patients after cardiovascular intervention can not only significantly reduce the damage of renal function caused by contrast agent,but also reduce the incidence of postoperative prognostic risk events to a certain extent.
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