营养干预结合不同运动方案在行同步放化疗食管癌患者中的应用效果  

Application effect of nutritional intervention combined with different exercise programs in esophageal cancer patients undergoing concurrent chemoradiotherapy

作　　者：朱晓丽 胡爱媛 陈香 ZHU Xiaoli;HU Aiyuan;CHEN Xiang(Tumor Hospital Affiliated to Nantong University,Nantong,Jiangsu,226361,China)

机构地区：[1]南通大学附属肿瘤医院,江苏南通226361

出　　处：《中西医结合护理（中英文）》2023年第5期33-36,共4页Journal of Clinical Nursing in Practice

摘　　要：目的探讨营养干预结合不同运动方案在行同步放射治疗和化学治疗(简称“放化疗”)食管癌患者中的临床效果。方法选取2020年6月至2021年12月在南通大学附属肿瘤医院行同步放化疗的90例食管癌患者为研究对象,以随机数字表法分为对照组和观察组,各45例。对照组给予营养干预结合步行运动,观察组给予营养干预结合抗阻运动,为期8周。比较2组患者的营养状况、骨骼肌质量、癌因性疲乏程度和生活质量。结果干预4周及8周后,2组的白蛋白和总蛋白水平均低于干预前(P均<0.05);但2组间在干预前后的白蛋白、总蛋白水平和身体质量指数经比较,差异均无统计学意义(P均>0.05)。干预8周后,2组的癌因性疲乏自评量表各维度评分均低于干预前,癌症患者生命质量测定量表各领域评分均优于干预前(P均<0.05);但2组在干预前后的上述评分经比较,差异均无统计学意义(P均>0.05)。2组在干预前及干预4周后的骨骼肌指数(SMI)经比较,差异均无统计学意义(P均>0.05);观察组在干预8周后的SMI高于对照组,差异有统计学意义(P<0.05)。结论营养干预结合不同运动方案均能改善行同步放化疗食管癌患者的营养状况、癌因性疲乏和生活质量,且营养干预结合抗阻运动还能增加患者的骨骼肌强度。Objective To explore the clinical effect of nutritional intervention combined with different exercise programs on esophageal cancer patients undergoing concurrent chemoradiotherapy.Methods A total of 90 esophageal cancer patients who underwent concurrent chemoradiotherapy at Tumor Hospital Affiliated to Nantong University from June 2020 to December 2021 were selected as the study subjects.They were allocated into a control group and an observation group by the use of a random number table,with 45 cases in each group.The control group received nutritional intervention combined with walking,while the observation group received nutritional intervention combined with resistance training.The intervention lasted for 8 weeks.The nutritional status,skeletal muscle mass,degree of cancer-related fatigue,and quality of life were compared between the two groups.Results After 4 and 8 weeks of intervention,the levels of albumin and total protein in both groups were lower than those before intervention(all P<0.05).There were no statistically significant differences in albumin,total protein,and body mass index between the two groups before and after intervention(all P>0.05).After 8 weeks of intervention,the scores of all dimensions of the cancerrelated fatigue self-rating scale in both groups were lower than those before intervention,and the scores of all dimensions of the European Organization for Research and Treatment of Cancer Core Quality of Life Questionnaire were better than those before intervention(all P<0.05).There were no statistically significant differences in the above scores between the two groups before and after intervention(all P>0.05).There were no statistically significant differences in skeletal muscle index(SMI)between the two groups before and after 4 weeks of intervention(both P>0.05).The SMI of the observation group was higher than that of the control group after 8 weeks of intervention,with significant difference(P<0.05).Conclusion Nutritional intervention combined with different exercise programs can i

关 键 词：食管癌 同步放射治疗和化学治疗 营养干预 运动方案 应用效果 

分 类 号：R473.73[医药卫生—护理学]