无机纳米材料用于糖尿病创口愈合的研究进展  

Progress of inorganic nanomaterials for diabetic wounds healing

作　　者：郑忠芹[1] 孟杰[2] ZHENG Zhong-qin;MENG Jie(Department of Endocrinology,Chengdu Municipal Xindu District People′s Hospital,Chengdu 610500,China;Emergency Department,the Second People′s Hospital of Chengdu Municipal Xindu District,Chengdu 610501,China)

机构地区：[1]成都市新都区人民医院内分泌科,四川成都610500 [2]成都市新都区第二人民医院急诊科,四川成都610501

出　　处：《西南民族大学学报（自然科学版）》2023年第4期401-407,共7页Journal of Southwest Minzu University(Natural Science Edition)

摘　　要：糖尿病患者存在糖代谢异常,导致机体长时间处于过度氧化应激、持续炎症、血管神经病变以及细菌感染,使其创面往往愈合不良.随着纳米技术的高速发展,纳米材料响应糖尿病创口愈合的特殊生理过程,提供个性化治疗方案备受关注.通过深入分析糖尿病创口愈合不良的原因,以及无机纳米材料具有的独特的模拟酶特性,总结各种无机纳米材料在促进糖尿病创面愈合的作用机理.Due to abnormal glucose metabolism in diabetic patients resulting in prolonged excessive oxidative stress,persistent inflammation,vascular neuropathy,and bacterial infection,their wounds often heal poorly.With the rapid development of nanotechnology,nanomaterials responding to the special physiological process of diabetic wounds healing and the provision of personalized treatment solutions are of great interest.Therefore,this paper deeply analyzes the causes of poor healing of diabetic wounds,and summarizes the mechanism of various inorganic nanomaterials in promoting diabetic wound healing based on their unique enzyme-mimicking properties.

关 键 词：无机纳米材料 糖尿病创口愈合 

分 类 号：R318[医药卫生—生物医学工程]