贵州省农村老年人睡眠质量与认知功能的关系及抑郁的中介作用  

Relationship between sleep quality and cognitive function and the mediating role of depression for older adults in the rural areas of Guizhou Province

作　　者：熊燕 杨敬源[1] 周全湘 屈芳 陈明燕 杨曦 杨星[1] XIONG Yan;YANG Jingyuan;ZHOU Quanxiang;QU Fang;CHEN Mingyan;YANG Xi;YANG Xing(Department of Epidemiology and Health Statistics,School of Public Health,Guizhou Medical University,Guiyang 550025,China)

机构地区：[1]贵州医科大学公共卫生与健康学院流行病与卫生统计学系,贵阳550025

出　　处：《中华疾病控制杂志》2023年第6期645-649,661,共6页Chinese Journal of Disease Control & Prevention

基　　金：国家自然科学基金(81760613);贵州省卫生健康委员会科学技术基金项目(gzwjkj2019-1-224)。

摘　　要：目的了解贵州省农村老年人睡眠质量对认知功能的影响,并分析抑郁状态在其中的中介作用。方法采用一般资料调查表、简易精神状态检测量表(mini-mental state examination,MMSE)、阿森斯失眠量表(Athens insomnia scale,AIS)和患者健康问卷-2(the patient health questionnaire-2,PHQ-2)对1615名贵州省农村老年人进行调查。构建结构方程模型(structural equation model,SEM)分析抑郁状态在睡眠质量与认知功能间的中介作用。结果不同性别、年龄、职业、婚姻状况及文化程度的老年人,其认知功能差异有统计学意义(均P<0.001)。睡眠质量与认知功能存在直接关联(β=-0.061,95%CI:-0.109~-0.015),并存在由抑郁状态介导的间接关联(β=-0.113,95%CI:-0.203~-0.024),且抑郁状态的相对中介效应(64.94%)大于睡眠质量对认知功能的直接效应(35.06%)。结论贵州省农村老年人睡眠质量与认知功能密切相关,抑郁状态可能是它们之间重要的中介因素。Objective This research seeks to examine how sleep quality influences the cognitive function of elderly individuals in rural areas of Guizhou Province,with a particular focus on the mediating role of depression.Methods We conducted a survey on 1615 older adults living in rural areas of Guizhou Province using a general data questionnaire,the mini-mental state examination(MMSE),the Athens insomnia scale(AIS),and the patient health questionnaire-2(PHQ-2).The structural equation model(SEM)was used to analyze the indirect effect of depression on the relationship between sleep quality and cognitive function.Results There were significant differences in cognitive function among older adults with different gender,ages,occupations,marital statuses,and educational levels(all P<0.001).A direct association was identified between sleep quality and cognitive function(β=-0.061,95%CI:-0.109-0.015),and depression displayed an indirect association between sleep quality and cognitive function(β=-0.113,95%CI:-0.203-0.024).In addition,the mediating effect of depression(64.94%)on the correlation between sleep quality and cognitive function was greater than the direct effect of sleep quality on cognitive function(35.06%).Conclusions Sleep quality significantly affects the cognitive function of elderly individuals in rural areas of Guizhou Province.Additionally,depression plays a crucial mediating role in the relationship between sleep quality and cognitive function.

关 键 词：睡眠质量 抑郁状态 认知功能 老年人 

分 类 号：R195.4[医药卫生—卫生统计学]