强化降糖治疗联合口腔行为学对2型糖尿病合并牙周炎患者的临床疗效分析  

Clinical Efficacy Analysis of Intensive Glucose-lowering Therapy Combined with Oral Behavior in Patients with Type 2 Diabetes Mellitus Combined with Periodontitis

作　　者：孙静 张丽娜 张娜 SUN Jing;ZHANG Li'na;ZHANG Na(Department of Municipal Party Committee Outpatient Clinic,Zibo Municipal Hospital,Zibo,Shandong Province,255000 China;Department of Laboratory,Zhangdian District People's Hospital,Zibo,Shandong Province,255000 China)

机构地区：[1]淄博市市级机关医院市委门诊部,山东淄博255000 [2]山东淄博市张店区人民医院检验科,山东淄博255000

出　　处：《糖尿病新世界》2023年第11期42-45,共4页Diabetes New World Magazine

摘　　要：目的观察强化降糖治疗联合口腔行为学对2型糖尿病合并牙周炎患者的临床疗效。方法选取2021年1—12月在淄博市市级机关医院市委门诊部口腔科确诊的牙周炎伴2型糖尿病患者100例。根据治疗方法不同分为观察组(51例)与对照组(49例)。对照组给予口腔行为治疗和降糖治疗,观察组在对照组的基础上,给予强化降糖治疗,随访1年,比较两组患者血糖指标[空腹血糖(FPG)、糖化血红蛋白(HbA1c)、血糖波动]及牙周健康指标[菌斑指数(PLI)、探诊深度(PD)、附着丧失(AL)]。结果治疗后,观察组FPG、HbA1c、平均血糖波动水平低于对照组,差异有统计学意义(t=16.61、13.25、23.31,P<0.05)。治疗后,观察组PLI、PD、AL水平低于对照组,差异有统计学意义(t=10.98、19.48、9.58,P<0.05)。结论牙周炎伴2型糖尿病的患者通过强化降糖治疗联合口腔行为学干预,血糖控制稳定,有利于疾病的恢复。Objective To observe the clinical efficacy of intensive glucose-lowering therapy combined with oral behavior in patients with type 2 diabetes mellitus combined with periodontitis.Methods From January to December 2021,100 patients with periodontal disease and type 2 diabetes diagnosed in the department of stomatology of the outpatient department of Zibo Municipal Government Hospital were selected.According to different treatment methods,they were divided into an observation group(51 cases)and a control group(49 cases).The control group was given oral behaviour therapy and hypoglycemic therapy,and the observation group was given intensive hypoglycemic therapy on the basis of the control group,followed up for one year,and compared the blood glucose indicators[fasting plasma glucose(FPG),glycated hemoglobin(HbA1c),blood glucose fluctuations]and periodontal health indicators[plaque index(PLI),depth of exploration(PD),and attachment loss(AL)]between the two groups.Results After treatment,the FPG,HbA1c,and average blood glucose fluctuation levels in the observation group were lower than those in the control group,and the difference was statistically significant(t=16.61,13.25,23.31,P<0.05).After treatment,the levels of PLI,PD,and AL in the observation group were lower than those in the control group,and the difference was statistically significant(t=10.98,19.48,9.58,P<0.05).Conclusion Patients with periodontitis with type 2 diabetes mellitus were treated with intensive glucose-lowering therapy combined with oral behavioral intervention,and the control of blood glucose was stable,which facilitated the recovery of the disease.

关 键 词：强化降糖治疗联合口腔行为学 2型糖尿病 牙周炎 临床疗效 

分 类 号：R4[医药卫生—临床医学]