Impact of contraceptive hormones on the reproductive potential of male and female commensal black rats (Rattus rattus)  

作　　者：Mwajabu SELEMANI Rhodes H.MAKUNDI Apia W.MASSAWE Ginethon MHAMPHI Loth S.MULUNGU Steven R.BELMAIN 

机构地区：[1]Department of Wildlife Management,Sokoine University of Agriculture,Morogoro,Tanzania [2]Pest Management Centre,Sokoine University of Agriculture,Morogoro,Tanzania [3]Natural Resources InstituteUniversity of Greenwich,Kent,UK

出　　处：《Integrative Zoology》2022年第6期991-1001,共11页整合动物学（英文版）

基　　金：funded by the African Union/European Development Fund(EcoRodMan:AURGII/1/006/2016);support from the International Partnership Programme of the Chinese Academy of Sciences(Grant No.152111KYSB20160089)。

摘　　要：The black rat is considered one of the world’s top pests.With increased restrictions on rodenticides,new alternatives to manage rats are urgently needed.Research on the use of contraceptive hormones,levonorgestrel(LE),and quinestrol(QU),have been evaluated against some rodent species,and this research is thefirst study to assess these on black rats.Hormones were incorporated into rodent bait at 10 and 50 ppm concentrations singly and in combination(EP-1).Groups of 10 animals of each sex were fed the baits over 7 days.Lower bait consumption was observed with slight body mass reductions.On dissection,it was observed that the uterus was in a state of edema and male reproductive organs weighed less with reduced sperm counts/motility.The 2 most promising baits,50 ppm QU and EP-1,were used to assess impact on pregnancy and litter size.Pregnancy was reduced from 70%success when both males and females consumed untreated bait,down to 30%when males had consumed contraceptive bait but females had not,and down to 0%when females had consumed contraceptive bait,regardless of whether they had paired with a treated or untreated male.Litter size in the untreated pairs was 8 pups,but only 4 pups in those cases where the male only had consumed the contraceptive.Further studies should investigate how long the effect lasts and its reversibility.Field studies at the population level may also shed light on the practicality of using contraceptive baits for black rats in different habitats.

关 键 词：contraceptive bait ecologically based rodent management fertility control LEVONORGESTREL QUINESTROL 

分 类 号：S76[农业科学—森林保护学]