沙美特罗替卡松气雾剂吸入治疗对老年慢性阻塞性肺疾病患者的临床疗效观察  

Clinical Observation of Salmeterol-Ticasone Aerosol Inhalation Therapy on Elderly Patients with Chronic Obstructive Pulmonary Disease

作　　者：杨玲美 马亮[1] Yang Ling-mei;Ma Liang(Department of General Medicine,Nantong Third People's Hospital,Nantong 226000,Jiangsu Province,China)

机构地区：[1]南通市第三人民医院全科医学科,江苏南通226000

出　　处：《中外医药研究》2023年第6期64-66,共3页JOURNAL OF CHINESE AND FOREIGN MEDICINE AND PHARMACY RESEARCH

摘　　要：目的:分析沙美特罗替卡松气雾剂吸入治疗对老年慢性阻塞性肺疾病患者的临床效果。方法:选取2018年1月—2022年1月南通市第三人民医院收治的老年慢性阻塞性肺疾病患者80例为研究对象,以随机数字表法分为对照组和观察组,各40例。对照组采取常规西医治疗,观察组在对照组基础上应用沙美特罗替卡松气雾剂吸入治疗。比较两组治疗效果、肺功能指标、生活质量、炎性因子水平。结果:观察组治疗有效率高于对照组,差异有统计学意义(P=0.025);治疗后,观察组用力肺活量、第1秒用力呼吸容积及呼气流量峰值水平高于对照组,差异有统计学意义(P<0.05);观察组躯体疼痛、角色受限、感情因素、生命活力、精神健康、社交能力、活动能力及总体健康评分高于对照组,差异有统计学意义(P<0.001)。治疗后,两组白介素-4、白介素-6、肿瘤坏死因子-α水平下降,观察组低于对照组,差异有统计学意义(P<0.05)。结论:沙美特罗替卡松气雾剂吸入治疗对老年慢性阻塞性肺疾病患者的临床效果显著,可改善患者肺功能、炎性因子水平,提高生活质量。Objective:To analyze the clinical effect of salmeterol-ticasone aerosol inhalation therapy on elderly patients with chronic obstructive pulmonary disease.Methods:Eighty elderly patients with chronic obstructive pulmonary disease admitted to Nantong Third People's Hospital from January 2018 to January 2022 were selected as the research objects.They were divided into control group and observation group by random number table method,with forty cases in each group.The control group was treated with conventional western medicine,and the observation group was treated with salmeterol-ticasone aerosol inhalation on the basis of the control group.The treatment effect,pulmonary function index,quality of life and inflammatory factor levels were compared between the two groups.Results:The effective rate of treatment in the observation group was higher than that in the control group,and the difference was statistically significant(P=0.025).After treatment,the forced vital capacity,forced respiratory volume in the first second,and peak expiratory flow in the observation group were higher than those in the control group,and the difference was statistically significant(P<0.05).The physical pain,role limitation,emotional factors,vitality,mental health,social ability,activity ability and overall health scores of the observation group were higher than those of the control group,and the difference was statistically significant(P<0.001).After treatment,the levels of interleukin-4,interleukin-6 and tumor necrosis factor-αin the two groups decreased,and the levels in the observation group were lower than those in the control group,and the difference was statistically significant(P<0.05).Conclusion:Salmeterol-ticasone aerosol inhalation therapy has a significant clinical effect on elderly patients with chronic obstructive pulmonary disease,which can improve the lung function,inflammatory factor levels and quality of life of the patients.

关 键 词：沙美特罗替卡松气雾剂 慢性阻塞性肺疾病 吸入治疗 老年 

分 类 号：R47[医药卫生—护理学]