西门塔尔牛常见遗传缺陷及其分子机制研究进展  

Advances in the Common Genetic Defects and Their Molecular Mechanisms in Simmental Cattle

作　　者：张可 欧四海[2] 司敬方 杨阳[2] 赵宗胜[3] 赵康 许维 柳咏雪 王雅春[1] 张毅[1] ZHANG Ke;OU Sihai;SI Jingfang;YANG Yang;ZHAO Zongsheng;ZHAOKang;XU Wei;LIU Yongxue;WANG Yachun;ZHANG Yi(College of Animal Science and Technology,China Agricultural University,Beijing 100193,China;Shihezi Animal Husbandry and Veterinary Workstation,The Eighth Division of Xinjiang Production and Construction Corps,Xinjiang Shihezi 832000,China;College of Animal Science and Technology,Shihezi University,Xinjiang Shihezi 832000,China;Tianjin Jialihe Livestock Production Corps,Tianjin 300409,China)

机构地区：[1]中国农业大学动物科学技术学院,北京100193 [2]新疆生产建设兵团第八师石河子市畜牧兽医工作站,新疆石河子832000 [3]石河子大学动物科技学院,新疆石河子832000 [4]天津嘉立荷牧业集团有限公司,天津300409

出　　处：《中国畜牧杂志》2023年第7期40-45,共6页Chinese Journal of Animal Science

基　　金：新疆生产建设兵团科技计划项目(2021AA004);财政部和农业农村部:国家现代农业产业技术体系(CARS36);天津市科技计划项目(19ZXZYSN00130)。

摘　　要：西门塔尔牛是生产性能优良且适应性强的乳肉兼用型牛品种。近年来,随着基因组检测芯片和全基因组测序技术的应用,国内外学者在西门塔尔牛中鉴定出多种新的遗传缺陷。本文综述了西门塔尔牛13种遗传缺陷的表型特征及分子机制研究进展,提示我国在引种和遗传改良过程中进行科学有效的遗传缺陷风险管理的必要性,也为我国牛育种中有害基因的准确筛查和逐步淘汰提供了科学资料。Simmental cattle is a milk-meat dual-purpose cattle breed with outstanding production performance,roughage tolerance and strong disease resistance.In recent years,with the application of genomic SNP chip and whole genome sequencing technology,scientists have identified a number of new genetic defects in Simmental cattle.This paper reviews the phenotypic characteristics and molecular mechanisms of 13 genetic defects reported in Simmental cattle,which highlights the importance of genetic risk management and mating program development and provides scientific data for diagnosis and genetic management of these harmful genes in cattle breeding in China.

关 键 词：西门塔尔牛 遗传缺陷 单倍型 隐性遗传 

分 类 号：S823.2[农业科学—畜牧学]