老年女性桡骨远端C型骨折与骨密度的相关性及术后抗骨质疏松治疗的临床效果  

Correlation between bone mineral densityy(BMD)and type C fractures of distal radius in elderly women,and the clinical effect of postoperative anti-osteoporosis treatment

作　　者：胡雷鸣 欧学海 Hu Leiming;Ou Xuehai(Ward 1,Hand Center,the Affiliated Honghui Hospital of Xi'an Jiaotong University,Xi'an 710054,China)

机构地区：[1]西安交通大学附属红会医院手外中心一病区,710054

出　　处：《美中国际创伤杂志》2023年第2期20-23,共4页U.S.Chinese International Journal of Traumatology

摘　　要：目的:研究老年女性桡骨远端AO分型、C型骨折与骨密度(BMD)的相关性及术后抗骨质疏松治疗的临床效果,为老年女性桡骨远端复杂关节内骨折的防治提供理论依据。方法:2019年2月至2021年2月我科共收集老年女性桡骨远端C型骨折105例为实验组,平均年龄63.5岁,随机分成两组,A组在进行常规桡骨远端骨折手术同时应用钙剂;B组在进行常规桡骨远端骨折手术同时应用钙剂+鲑鱼降钙素,抗骨质疏松治疗疗程均为1年。100名未发生桡骨远端骨折的老年女性为对照组。所有患者均获得随访,应用DEXA分别对患者腰椎和髋部的BMD进行检测;摄X线片以了解桡骨远端骨折愈合情况及全身其他部位再次发生与骨质疏松相关骨折情况,所得数据进行统计学分析。结果:在所有发生桡骨远端C型骨折的老年女性中85.2%腰椎和髋部的BMD降低,诊断为骨质疏松症者为62.4%,较对照组减低,差异具有显著性意义(P<0.05);A、B两组之间BMD差异无显著性意义(P>0.05)。术后1年,A组患者腰椎和髋部BMD有不同程度的降低,而B组患者腰椎和髋部的BMD有不同程度的升高,两组之间的差别有显著性(P<0.05);首次骨折2年内A组患者全身其他部位(股骨颈、腰椎)再次发生与骨质疏松相关的骨折8例,再骨折率15.1%;B组患者发生再骨折3例,再骨折率5.7%。结论:老年女性桡骨远端C型骨折与腰椎、髋部BMD降低具有明显的相关性,在进行骨折手术治疗同时应用钙剂+鲑鱼降钙素抗骨质疏松治疗能更好地降低再骨折的发生。Objective:To study the relationship between bone mineral density(BMD)and AO classification of distal radius,type C fracture and the clinical effect of anti-osteoporosis therapy in elderly women,to provide a theoretical basis for the prevention and treatment of complex intra-articular fractures of distal radius in elderly women.Methods:From February 2019 to February 2021,a total of 105 cases of type C fracture of distal radius in old women were collected as experimental group,with an average age of 63.5.they were randomly divided into two groups,group A was treated with calcium during routine distal radius fracture operation,and the patients in group B were treated with calcium and salmon calcitonin at the same time,and the course of treatment was 1 year.A total of 100 elderly women without distal radius fractures served as controls.All patients were followed up and DEXA was used to measure BMD of the lumbar spine and hip.X-ray films were taken to understand the healing of distal radius fractures and other parts of the body reoccurrence of osteoporosis-related fractures.The data were analyzed statistically.Results:BMD of lumbar spine and hip decreased in 85.2%of all aged women with type C fractures of distal radius,and in 62.4%of those diagnosed as osteoporosis,which was significantly lower than that in the control group(P<0.05).There was no significant difference in BMD between group A and group B(P>0.05).One year after operation,BMD of lumbar spine and hip in group A decreased to some extent,while BMD of lumbar spine and hip in group B increased to some extent,The difference between the two groups was significant(P<0.05).In Group A,8 cases(15.1%)of osteoporosis-related fractures occurred in other parts of the body(neck of femur,lumbar spine)within 2 years after the first fracture,refracture occurred in 3 cases(5.7%)in Group B.Conclusion:Type C fractures of distal radius in elderly women were significantlyassociatedwith lower BMD of lumbar spine and hip,Calcium and salmon calcitonin can reduce the incidence of re

关 键 词：老年女性 桡骨远端C型骨折 骨密度(BMD) 抗骨质疏松治疗 

分 类 号：R68[医药卫生—骨科学]