2014—2020年血液成分制备技术的应用现状分析  

Application status analysis of blood component preparation techniques from 2014 to 2020

作　　者：陈冬梅[1] 赵国庆[2] 尹鲲 李莹[4] 李小春[5] 韩卫[6] 李涛[7] 张旸 孟跟东 杜霞[10] 韩璐[11] 曾北南 李苗苗 刘妍妍 王林[15] 白林 邱艳[17] Chen Dongmei;Zhao Guoqing;Yin Kun;Li Ying;Li Xiaochun;Han Wei;Li Tao;Zhang Yang;Meng Gendong;Du Xia;Han Lu;Zeng Beinan;Li Miaomiao;Liu Yanyan;Wang Lin;Bai Lin;Qiu Yan(Department of Blood Transfusion Safety Research Section,Beijing Red Cross Blood Center,Beijing 100088,China)

机构地区：[1]北京市红十字血液中心安全输血研究室,100088 [2]黑龙江省血液中心办公室 [3]山东省血液中心办公室 [4]江西省血液中心业务科 [5]成都市血液中心血液制备科 [6]河北省血液中心检验科 [7]长沙血液中心科教信息科 [8]广州血液中心业务管理部 [9]辽宁省血液中心成分科 [10]云南昆明血液中心业务科 [11]武汉血液中心质量控制科 [12]重庆市血液中心成分制备科 [13]江苏省血液中心成分制备科 [14]天津市血液中心办公室 [15]海南省血液中心业务科 [16]太原市血液中心办公室 [17]北京市红十字血液中心办公室

出　　处：《北京医学》2023年第4期351-355,共5页Beijing Medical Journal

摘　　要：目的 探讨2014—2020年血液成分制备技术的应用现状。方法 选取2014—2020年我国采供血机构执业比对平台血液中心16家,分析其具有旁路系统的血袋耗材、去除白细胞、血液辐照和血浆成分病原体灭活技术的应用情况。结果 16家血液中心中,11家(68.75%)采集全血使用旁路系统分流前端血液。14家(87.50%)开展红细胞成分血储存前去除白细胞,其中去白细胞悬浮红细胞的质控抽检结果显示,200 ml规格白细胞残留量平均值为(0.18~0.42)×106/袋,300 ml规格的平均值为(0.22~0.33)×10~6/袋,400 ml规格的平均值为(0.78~0.86)×106/袋。16家(100.00%)单采血小板均去除白细胞。12家(75.00%)进行红细胞成分血和血小板成分血发放前辐照,辐照技术使用率呈现较大差异。11家(68.75%)血浆成分血进行病原体灭活处理。结论 具有旁路系统的血袋分流前端血液、去除白细胞、辐照和病原体灭活等血液成分制备技术的使用率在不同血液中心呈现较大差异,应用血液成分制备技术预防输血传染病的空间有待进一步提升。Objective To explore the application status of blood component preparation techniques.Methods A total of 16 blood centers of blood collection and supply institutions from 2014 to 2020 were selected,the application of blood bag consumables with bypass system,leukocyte removal technology,blood irradiation and plasma component pathogen inactivation technology were analyzed.Results Diversion pouch was applied in 11(68.75%) blood centers while collecting whole blood.Leukocyte reduction of red cells before storage was applied in 14(87.50%) blood centers.The leukocyte residue of red blood cells in additive solution leukocyte reduced were(0.18 ~ 0.42) × 106/bag in 200 ml,(0.22 ~ 0.33) × 106/bag in300 ml,(0.78 ~ 0.86) × 106/bag in 400 ml.Leukocyte reduction of apheresis platelet was applied in 16 blood centers.Irradiation of red cells and platelets prior to issue was applied in 12(75.00%) blood centers,but there was great difference in the use rate of irradiation among the above blood centers.Pathogen inactivation of plasma was applied in 11(68.75%) blood centers.Conclusions The preparation capability of blood components is different in different blood centers,such as using diversion pouch,leukocyte reduction,irradiation and pathogen inactivation.We should do more to improve blood component preparation techniques to reduce the residual risk of transfusion.

关 键 词：旁路系统 去除白细胞 辐照 病原体灭活 输血传染病 

分 类 号：R457.1[医药卫生—治疗学]