内蒙古汉族与蒙古族人群Rh血型对比分析调查  

Comparative analysis of Rh blood group between Han and Mongolian people in Inner Mongolia

作　　者：乔姝 余艳琴[1] 郝金奇[2] 解彩霞 吕瑞虹 郑晓娇 QIAO Shu;YU Yanqin;HAO Jinqi;XIE Caixia;LV Ruihong;ZHENG Xiaojiao(Department of Blood Transfusion,the First Affiliated Hospital of Baotou Medical College,Inner Mongolia University of Science and Technology,Baotou,014010,China;School of Public Health,Baotou Medical College,Inner Mongolia University of Science and Technology;Department of Laboratory,Erlianhot Central Hospital,Inner Mongolia)

机构地区：[1]内蒙古科技大学包头医学院第一附属医院输血科,内蒙古包头014010 [2]内蒙古科技大学包头医学院公共卫生学院 [3]内蒙古二连浩特市中心医院检验科

出　　处：《临床血液学杂志》2023年第6期432-435,共4页Journal of Clinical Hematology

基　　金：内蒙古自治区卫生健康委科研计划项目(No:201703161)。

摘　　要：目的:对内蒙古北部二连浩特市的蒙古族与中部包头市汉族Rh血型系统表型差异性进行研究,为内蒙古不同民族人群输血安全和精准输血提供参考。方法:运用微柱凝胶卡式法对内蒙古包头地区汉族住院患者1026例和二连浩特市医院住院纯蒙古族血统患者506例进行Rh表型血清学分型。结果:共检出11种Rh血型表型,汉族以CCDee和CcDEe表型居多,蒙古族CCDee和CcDEe表型居多。蒙古族CcDee表型频率占比高于汉族,ccDEE表型频率低于汉族,差异有统计学差异(P<0.05)。结论:内蒙古纯蒙古族血统患者同汉族患者人群在Rh血型分型上存在差异,蒙古族D、C、c、E、e抗原频率明显高于汉族人群,ee表型明显低于汉族人群,所以蒙古族人群在产生免疫性抗-E抗体频率要低于汉族人群,由抗-E抗体引起的输血反应和新生儿溶血疾病的风险低于汉族人群。Objective To study the phenotypic difference of Rh blood group system between the Mongolian nationality in Erenhot City in northern Inner Mongolia and the Han nationality in Baotou City in central Inner Mongolia,so as to provide a reference for the safety and precision blood transfusion of people in different regions of Inner Mongolia.Methods A total of 1026 cases of Han nationality in Baotou area of Inner Mongolia and 506 cases of pure Mongolian inpatients in Erenhot City Hospital were selected for serotyping of Rh phenotype.Results A total of 11 Rh blood group phenotypes were detected.The majority of the phenotypes were CCDee and CCDee in Han nationality,while the majority of the phenotypes were CCDee and CCDee in Mongolian nationality.The frequency of CCDee phenotype in Mongolian nationality was much higher than that in Han nationality,and the frequency of CCDee phenotype was much lower than that in Han nationality,and the difference was statistically significant(P<0.05).Conclusion In northern Inner Mongolia,pure Mongolian crowd have differences in Rh blood type classification,the Mongolian D,C,c,E,e antigen frequency obviously higher than that of the Han people,generally ee phenotypic significantly lower than that of the Han Chinese population,which can be concluded that in the Mongolian people,the frequency of immune anti-E antibodies would be lower than that of the han people,and the risk of transfusion reactions and neonatal hemolytic disorders caused by anti-E antibodies would be lower than that in the Han population.

关 键 词：内蒙古 汉族 蒙古族 RH血型 调查 

分 类 号：R457.1[医药卫生—治疗学]