紫花地丁药理作用研究进展  

Research Progress on the Pharmacological Effects of Viola yedoensis Makino

作　　者：李媛媛[1] 毛妍 梁曾恩妮 杨成林 邬静[1] 袁志航[1] 袁莉芸 LI Yuanyuan;MAO Yan;LIANG Zengenni;YANG Chenglin;WU Jing;YUAN Zhihang;YUAN Liyun(Hunan Agricultural University,Changsha 410128,China;Xiangyang Polytechnic,Xiangyang 441050,China;Hunan Agricultural Products Processing Insitute,Hunan Academy of Agricultural Sciences,Changsha 410128,China)

机构地区：[1]湖南农业大学,长沙410128 [2]襄阳职业技术学院,襄阳441050 [3]湖南省农业科学院农产品加工研究所,长沙410128

出　　处：《中国畜牧兽医》2023年第7期2998-3006,共9页China Animal Husbandry & Veterinary Medicine

基　　金：湖北省教育厅项目(B2020397);湖南省教育厅青年项目(21B028);襄阳市科技计划项目(011158671/2021-31052)。

摘　　要：紫花地丁是堇菜科植物,又被称为辽堇菜、野堇菜、光瓣堇菜等,其用药历史悠久,是中国传统的中草药植物,其味苦、辛、寒,归心、肝经,具有清热解毒、凉血消肿、清热利湿的作用,主治疔疮、痈肿、瘰疬、黄疸、痢疾、腹泻等。近年来通过现代药理学研究以及在人和动物的临床治疗中显示出紫花地丁具有抗炎、抗菌、抗氧化等作用。另外,自2020年起,中国规定在饲料中全面禁止添加抗生素并禁用部分抗生素兽药,减少滥用抗生素造成的危害,维护动物源食品安全和公共卫生安全。而中兽药产品取自天然植物及动物,具有多组分、多功能、多靶点的优势,并且针对动物整个机体用药,而不是单纯地针对病原体用药。作者通过查阅国内外紫花地丁的相关药理作用研究资料,对紫花地丁的抗菌、抗炎、抗氧化、抗病毒、免疫调节、抗癌等药理作用的最新研究进展进行了综述,为后续紫花地丁作为中兽药或饲料添加剂的研究提供理论依据。Viola yedoensis Makino is a plant of Violaceae,also known as Viola liao,Viola wild,Viola glabra,etc.It has a long history of drug use and it is a traditional Chinese herbal medicine plant in China.It tastes bitter,pungent,cold,and has the functions of clearing heat,detoxification,cooling blood,detumescence,clearing heat and dampness.It is mainly used to treat boils,carbuncle,scrofula,jaundice,dysentery,diarrhea,etc.In recent years,it has been shown that Viola yedoensis Makino has anti-inflammatory,antibacterial,antioxidant and other effects through modern pharmacological research and clinical treatment of humans and animals.In addition,since 2020,China has stipulated that the addition of antibiotics and some antibiotic veterinary drugs are prohibited in feed,so as to reduce the harm caused by the abuse of antibiotics and maintain the safety of animal derived food and public health.Chinese veterinary medicine products are derived from natural plants and animals,and have the advantages of multi-component,multi-function and multi target.They are also used for the whole animal body,rather than purely for pathogens.Therefore,the author reviewed the latest research progress of the pharmacological effects of Viola yedoensis Makino,such as antibacterial,anti-inflammatory,anti-oxidation,anti-virus,immune regulation,anti-cancer and so on,and it provides a theoretical basis for the subsequent research of Viola yedoensis Makino as a Chinese veterinary drug or feed additive.

关 键 词：紫花地丁 抗菌 免疫调节 抗炎 抗氧化 抗病毒 

分 类 号：S853.74[农业科学—临床兽医学]