Recent advances on the synthesis of natural pyrrolizidine alkaloids: alexine, and its stereoisomers  

作　　者：Ghodsi Mohammadi Ziarani Negar Jamasbi Fatemeh Mohajer 

机构地区：[1]Department of Chemistry,Faculty of Physics and Chemistry,Alzahra University,P.O.Box 1993893973,Tehran,Iran

出　　处：《Natural Products and Bioprospecting》2022年第1期26-40,共15页应用天然产物（英文）

摘　　要：Natural products have attracted the interest of the scientific community due to their importance and application.Alexine is a naturally polyhydroxylated pyrrolizidine alkaloid that is broadly found in plant sources and isolated from Alexa leiopetala.The biological properties such as glycosidase inhibitors,anti-virus,and anti-HIV activities,makes it interesting target for synthetical studies.This review reports different approaches and methodologies to the synthesis of alexine,and its stereoisomers as the target compounds in numerous studies.

关 键 词：Polyhydroxylated pyrrolizidine alkaloids Alexine Natural products Alexa leiopetala 

分 类 号：O62[理学—有机化学]