Three new pyrrole alkaloids from the endophytic fungus Albifimbria viridis  

作　　者：Pan-Pan Wei Jia-Cheng Ji Xu-Jun Ma Zheng-Hui Li Hong-Lian Ai Xin-Xiang Lei Ji-Kai Liu 

机构地区：[1]School of Pharmaceutical Sciences,South-Central University for Nationalities,Wuhan 430074,People’s Republic of China

出　　处：《Natural Products and Bioprospecting》2022年第1期51-55,共5页应用天然产物（英文）

基　　金：National Natural Science Foundation of China (31870513);Zheng-Hui Li,National Aerospace Science Foundation of China (32000011),Hong-Lian Ai.

摘　　要：Three new pyrrole alkaloids albifipyrrols A-C(1-3),were isolated from the endophytic fungus Albifimbria viridis col-lected from the Chinese medicinal plant.Their structures were elucidated by extensive NMR and HRESIMS spectro-metric analyses.All compounds were evaluated for immunosuppressive activity.Fortunately,compound 2 exhibits certain inhibition specifically against the LPS-induced proliferation of B lymphocyte cells with IC50 value 16.16μM.

关 键 词：Pyrrole alkaloids Coptis chinensis Endophytic fungus Albifimbria viridis Immunosuppressive activity 

分 类 号：O62[理学—有机化学]