星状神经节阻滞应用时机对颅内动脉瘤夹闭术后的影响  

Effect of the timing of stellate ganglion block on intracranial aneurysm clipping

作　　者：孟彩霞 高雁华[1] MENG Caixia;GAO Yanhua(Department of Anesthesiology,People's Hospital of Anyang,Anyang,Henan 455099,China)

机构地区：[1]河南省安阳市人民医院麻醉科,河南安阳455099

出　　处：《中国医学工程》2023年第7期104-107,共4页China Medical Engineering

摘　　要：目的探究星状神经节阻滞(SGB)应用时机对颅内动脉瘤夹闭术后的影响。方法选取2021年2月至2022年8月在安阳市人民医院收治的实施颅内动脉瘤夹闭术的96例患者作为研究对象,根据就诊顺序分配编号,按照随机数字表法分成对照组(32例)、术前阻滞组(32例)和术后阻滞组(32例)。三组患者均实施常规全身麻醉,其中对照组不实施SGB,术前阻滞组在麻醉诱导前实施SGB,术后阻滞组在术后即时实施SGB。比较三组患者的大脑中动脉(MCA)平均血流速度、神经元特异性烯醇化酶(NSE)与β-内啡肽水平(β-EP)和术后并发症。结果治疗前三组患者MCA平均血流速度、NSE和β-EP比较,差异无统计学意义(P>0.05)。术后24 h,术前阻滞组患者的MCA平均血流速度、NSE和β-EP改善优于对照组和术后阻滞组(P<0.05)。结论对颅内动脉瘤夹闭患者术前、术后行SGB均有助于预后恢复,而术前阻滞较术后阻滞效果更明显,为术前行SGB提供了一定的临床依据。【Objective】To investigate the effect of the timing of stellate ganglion block(SGB)on intracranial aneurysm clipping.【Methods】Ninety six patients who underwent intracranial aneurysm clipping in our hospital from February 2021 to August 2022 were selected as the study objects.According to the order of treatment,every patient was assigned a number,and they were randomly divided into control group(32 cases),preoperative block group(32 cases),and postoperative block group(32 cases).All patients in the three groups received routine general anesthesia.The control group did not receive SGB,the preoperative block group received SGB before anesthesia induction,and the postoperative block group received SGB immediately after surgery.The mean blood flow velocity of middle cerebral artery(MCA),the levels of neuron specific enolase(NSE)andβ-endorphin(β-EP),and postoperative complications were compared among the three groups.【Results】There was no significant difference in MCA mean blood flow velocity,NSE andβ-EP among the three groups before treatment(P>0.05).At 24 hours after operation,the improvement of MCA mean blood flow velocity,NSE and EP in the preoperative block group was better than that in the control group and the postoperative block group(P<0.05).【Conclusion】SGB is helpful to the prognosis of patients with intracranial aneurysm clipping before and after operation,and the preoperative block is more effective than the postoperative block,which provides a certain clinical basis for preoperative SGB.

关 键 词：星状神经节阻滞 颅内动脉瘤 大脑中动脉平均血流速度 神经元特异性烯醇化酶 Β-内啡肽 

分 类 号：R614[医药卫生—麻醉学]